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Long-term safety and efficacy of givinostat in polycythemia vera: 4-year mean follow up of three phase 1/2 studies and a compassionate use program.
Rambaldi A, Iurlo A, Vannucchi AM, Martino B, Guarini A, Ruggeri M, von Bubnoff N, De Muro M, McMullin MF, Luciani S, Martinelli V, Nogai A, Rosti V, Ricco A, Bettica P, Manzoni S, Di Tollo S. Rambaldi A, et al. Among authors: von bubnoff n. Blood Cancer J. 2021 Mar 6;11(3):53. doi: 10.1038/s41408-021-00445-z. Blood Cancer J. 2021. PMID: 33677466 Free PMC article. Clinical Trial.
Safety and efficacy of the maximum tolerated dose of givinostat in polycythemia vera: a two-part Phase Ib/II study.
Rambaldi A, Iurlo A, Vannucchi AM, Noble R, von Bubnoff N, Guarini A, Martino B, Pezzutto A, Carli G, De Muro M, Luciani S, McMullin MF, Cambier N, Marolleau JP, Mesa RA, Tibes R, Pancrazzi A, Gesullo F, Bettica P, Manzoni S, Di Tollo S. Rambaldi A, et al. Among authors: von bubnoff n. Leukemia. 2020 Aug;34(8):2234-2237. doi: 10.1038/s41375-020-0735-y. Epub 2020 Feb 11. Leukemia. 2020. PMID: 32047238 Free PMC article. Clinical Trial. No abstract available.
Activity of therapeutic JAK 1/2 blockade in graft-versus-host disease.
Spoerl S, Mathew NR, Bscheider M, Schmitt-Graeff A, Chen S, Mueller T, Verbeek M, Fischer J, Otten V, Schmickl M, Maas-Bauer K, Finke J, Peschel C, Duyster J, Poeck H, Zeiser R, von Bubnoff N. Spoerl S, et al. Among authors: von bubnoff n. Blood. 2014 Jun 12;123(24):3832-42. doi: 10.1182/blood-2013-12-543736. Epub 2014 Apr 7. Blood. 2014. PMID: 24711661 Free article.
Ruxolitinib in GvHD (RIG) study: a multicenter, randomized phase 2 trial to determine the response rate of Ruxolitinib and best available treatment (BAT) versus BAT in steroid-refractory acute graft-versus-host disease (aGvHD) (NCT02396628).
von Bubnoff N, Ihorst G, Grishina O, Röthling N, Bertz H, Duyster J, Finke J, Zeiser R. von Bubnoff N, et al. BMC Cancer. 2018 Nov 19;18(1):1132. doi: 10.1186/s12885-018-5045-7. BMC Cancer. 2018. PMID: 30453910 Free PMC article. Clinical Trial.
Ruxolitinib for Glucocorticoid-Refractory Acute Graft-versus-Host Disease.
Zeiser R, von Bubnoff N, Butler J, Mohty M, Niederwieser D, Or R, Szer J, Wagner EM, Zuckerman T, Mahuzier B, Xu J, Wilke C, Gandhi KK, Socié G; REACH2 Trial Group. Zeiser R, et al. Among authors: von bubnoff n. N Engl J Med. 2020 May 7;382(19):1800-1810. doi: 10.1056/NEJMoa1917635. Epub 2020 Apr 22. N Engl J Med. 2020. PMID: 32320566 Clinical Trial.
Integrative molecular profiling identifies two molecularly and clinically distinct subtypes of blastic plasmacytoid dendritic cell neoplasm.
Künstner A, Schwarting J, Witte HM, Bernard V, Stölting S, Kusch K, Nagarathinam K, von Bubnoff N, Murga Penas EM, Merz H, Busch H, Feller AC, Gebauer N. Künstner A, et al. Among authors: von bubnoff n. Blood Cancer J. 2022 Jul 4;12(7):101. doi: 10.1038/s41408-022-00699-1. Blood Cancer J. 2022. PMID: 35788129 Free PMC article. No abstract available.
Activated granulocytes and inflammatory cytokine signaling drive T-cell lymphoma progression and disease symptoms.
Jaeger A, Gambheer SMM, Sun X, Chernyakov D, Skorobohatko O, Mack T, Kissel S, Pfeifer D, Zeiser R, Fisch P, Andrieux G, Bräuer-Hartmann D, Bauer M, Schulze S, Follo M, Boerries M, von Bubnoff N, Miething C, Hidalgo JV, Klein C, Weber T, Wickenhauser C, Binder M, Dierks C. Jaeger A, et al. Among authors: von bubnoff n. Blood. 2023 Jun 8;141(23):2824-2840. doi: 10.1182/blood.2022015653. Blood. 2023. PMID: 36696631
Prognosis of patients with primary central nervous system lymphoma after high-dose chemotherapy followed by autologous stem cell transplantation.
Schorb E, Kasenda B, Atta J, Kaun S, Morgner A, Hess G, Elter T, von Bubnoff N, Dreyling M, Ringhoffer M, Krause SW, Derigs G, Klimm B, Niemann D, Fritsch K, Finke J, Illerhaus G. Schorb E, et al. Among authors: von bubnoff n. Haematologica. 2013 May;98(5):765-70. doi: 10.3324/haematol.2012.076075. Epub 2013 Jan 8. Haematologica. 2013. PMID: 23300179 Free PMC article.
149 results