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Peroxisome proliferator-activated receptor ɣ agonist mediated inhibition of heparanase expression reduces proteinuria.
Garsen M, Buijsers B, Sol M, Gockeln L, Sonneveld R, van Kuppevelt TH, de Graaf M, van den Born J, Kamps JAAM, van Raalte DH, van der Meer RW, Lamb HJ, Hillebrands JL, Rabelink TJ, Maciej-Hulme ML, Krenning G, Nijenhuis T, van der Vlag J. Garsen M, et al. Among authors: van den born j, van kuppevelt th, van der meer rw, van der vlag j, van raalte dh. EBioMedicine. 2023 Apr;90:104506. doi: 10.1016/j.ebiom.2023.104506. Epub 2023 Mar 6. EBioMedicine. 2023. PMID: 36889064 Free PMC article.
Heparan sulfate proteoglycans in glomerular inflammation.
Rops AL, van der Vlag J, Lensen JF, Wijnhoven TJ, van den Heuvel LP, van Kuppevelt TH, Berden JH. Rops AL, et al. Among authors: van kuppevelt th, van der vlag j, van den heuvel lp. Kidney Int. 2004 Mar;65(3):768-85. doi: 10.1111/j.1523-1755.2004.00451.x. Kidney Int. 2004. PMID: 14871397 Free article. Review.
Localization and functional characterization of glycosaminoglycan domains in the normal human kidney as revealed by phage display-derived single chain antibodies.
Lensen JF, Rops AL, Wijnhoven TJ, Hafmans T, Feitz WF, Oosterwijk E, Banas B, Bindels RJ, van den Heuvel LP, van der Vlag J, Berden JH, van Kuppevelt TH. Lensen JF, et al. Among authors: van kuppevelt th, van der vlag j, van den heuvel lp. J Am Soc Nephrol. 2005 May;16(5):1279-88. doi: 10.1681/ASN.2004050413. Epub 2005 Mar 23. J Am Soc Nephrol. 2005. PMID: 15788473 Free article.
Aberrant heparan sulfate profile in the human diabetic kidney offers new clues for therapeutic glycomimetics.
Wijnhoven TJ, Lensen JF, Rops AL, van der Vlag J, Kolset SO, Bangstad HJ, Pfeffer P, van den Hoven MJ, Berden JH, van den Heuvel LP, van Kuppevelt TH. Wijnhoven TJ, et al. Among authors: van den hoven mj, van kuppevelt th, van der vlag j, van den heuvel lp. Am J Kidney Dis. 2006 Aug;48(2):250-61. doi: 10.1053/j.ajkd.2006.05.003. Am J Kidney Dis. 2006. PMID: 16860191
Induction of glomerular heparanase expression in rats with adriamycin nephropathy is regulated by reactive oxygen species and the renin-angiotensin system.
Kramer A, van den Hoven M, Rops A, Wijnhoven T, van den Heuvel L, Lensen J, van Kuppevelt T, van Goor H, van der Vlag J, Navis G, Berden JH. Kramer A, et al. Among authors: van goor h, van kuppevelt t, van der vlag j, van den heuvel l, van den hoven m. J Am Soc Nephrol. 2006 Sep;17(9):2513-20. doi: 10.1681/ASN.2006020184. Epub 2006 Aug 9. J Am Soc Nephrol. 2006. PMID: 16899518 Free article.
In vivo degradation of heparan sulfates in the glomerular basement membrane does not result in proteinuria.
Wijnhoven TJ, Lensen JF, Wismans RG, Lamrani M, Monnens LA, Wevers RA, Rops AL, van der Vlag J, Berden JH, van den Heuvel LP, van Kuppevelt TH. Wijnhoven TJ, et al. Among authors: van kuppevelt th, van der vlag j, van den heuvel lp. J Am Soc Nephrol. 2007 Mar;18(3):823-32. doi: 10.1681/ASN.2006070692. Epub 2007 Jan 24. J Am Soc Nephrol. 2007. PMID: 17251387 Free article. Retracted.
Heparan sulfate on activated glomerular endothelial cells and exogenous heparinoids influence the rolling and adhesion of leucocytes.
Rops AL, Jacobs CW, Linssen PC, Boezeman JB, Lensen JF, Wijnhoven TJ, van den Heuvel LP, van Kuppevelt TH, van der Vlag J, Berden JH. Rops AL, et al. Among authors: van kuppevelt th, van der vlag j, van den heuvel lp. Nephrol Dial Transplant. 2007 Apr;22(4):1070-7. doi: 10.1093/ndt/gfl801. Epub 2007 Jan 25. Nephrol Dial Transplant. 2007. PMID: 17255131 Free article.
Adult and paediatric patients with minimal change nephrotic syndrome show no major alterations in glomerular expression of sulphated heparan sulphate domains.
Wijnhoven TJ, Geelen JM, Bakker M, Lensen JF, Rops AL, Kramer AB, Navis G, van den Hoven MJ, van der Vlag J, Berden JH, Wetzels JF, van den Heuvel LP, Monnens LA, van Kuppevelt TH. Wijnhoven TJ, et al. Among authors: van den hoven mj, van kuppevelt th, van der vlag j, van den heuvel lp. Nephrol Dial Transplant. 2007 Oct;22(10):2886-93. doi: 10.1093/ndt/gfm301. Epub 2007 May 25. Nephrol Dial Transplant. 2007. PMID: 17526541
208 results