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Page 1
Steroid receptor coactivator-1 modulates the function of Pomc neurons and energy homeostasis.
Yang Y, van der Klaauw AA, Zhu L, Cacciottolo TM, He Y, Stadler LKJ, Wang C, Xu P, Saito K, Hinton A Jr, Yan X, Keogh JM, Henning E, Banton MC, Hendricks AE, Bochukova EG, Mistry V, Lawler KL, Liao L, Xu J, O'Rahilly S, Tong Q; UK10K Consortium; Inês Barroso, O'Malley BW, Farooqi IS, Xu Y. Yang Y, et al. Among authors: van der klaauw aa. Nat Commun. 2019 Apr 12;10(1):1718. doi: 10.1038/s41467-019-08737-6. Nat Commun. 2019. PMID: 30979869 Free PMC article.
Obesity due to melanocortin 4 receptor (MC4R) deficiency is associated with increased linear growth and final height, fasting hyperinsulinemia, and incompletely suppressed growth hormone secretion.
Martinelli CE, Keogh JM, Greenfield JR, Henning E, van der Klaauw AA, Blackwood A, O'Rahilly S, Roelfsema F, Camacho-Hübner C, Pijl H, Farooqi IS. Martinelli CE, et al. Among authors: van der klaauw aa. J Clin Endocrinol Metab. 2011 Jan;96(1):E181-8. doi: 10.1210/jc.2010-1369. Epub 2010 Nov 3. J Clin Endocrinol Metab. 2011. PMID: 21047921
High protein intake stimulates postprandial GLP1 and PYY release.
van der Klaauw AA, Keogh JM, Henning E, Trowse VM, Dhillo WS, Ghatei MA, Farooqi IS. van der Klaauw AA, et al. Obesity (Silver Spring). 2013 Aug;21(8):1602-7. doi: 10.1002/oby.20154. Epub 2013 May 13. Obesity (Silver Spring). 2013. PMID: 23666746 Free PMC article. Clinical Trial.
KSR2 mutations are associated with obesity, insulin resistance, and impaired cellular fuel oxidation.
Pearce LR, Atanassova N, Banton MC, Bottomley B, van der Klaauw AA, Revelli JP, Hendricks A, Keogh JM, Henning E, Doree D, Jeter-Jones S, Garg S, Bochukova EG, Bounds R, Ashford S, Gayton E, Hindmarsh PC, Shield JP, Crowne E, Barford D, Wareham NJ; UK10K consortium; O'Rahilly S, Murphy MP, Powell DR, Barroso I, Farooqi IS. Pearce LR, et al. Among authors: van der klaauw aa. Cell. 2013 Nov 7;155(4):765-77. doi: 10.1016/j.cell.2013.09.058. Cell. 2013. PMID: 24209692 Free PMC article.
The hunger genes: pathways to obesity.
van der Klaauw AA, Farooqi IS. van der Klaauw AA, et al. Cell. 2015 Mar 26;161(1):119-132. doi: 10.1016/j.cell.2015.03.008. Cell. 2015. PMID: 25815990 Free article. Review.
The Sleep/Wake Cycle is Directly Modulated by Changes in Energy Balance.
Collet TH, van der Klaauw AA, Henning E, Keogh JM, Suddaby D, Dachi SV, Dunbar S, Kelway S, Dickson SL, Farooqi IS, Schmid SM. Collet TH, et al. Among authors: van der klaauw aa. Sleep. 2016 Sep 1;39(9):1691-700. doi: 10.5665/sleep.6094. Sleep. 2016. PMID: 27306267 Free PMC article. Clinical Trial.
Failure of sucrose replacement with the non-nutritive sweetener erythritol to alter GLP-1 or PYY release or test meal size in lean or obese people.
Overduin J, Collet TH, Medic N, Henning E, Keogh JM, Forsyth F, Stephenson C, Kanning MW, Ruijschop RMAJ, Farooqi IS, van der Klaauw AA. Overduin J, et al. Among authors: van der klaauw aa. Appetite. 2016 Dec 1;107:596-603. doi: 10.1016/j.appet.2016.09.009. Epub 2016 Sep 9. Appetite. 2016. PMID: 27620647 Free PMC article. Clinical Trial.
56 results