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Biallelic loss-of-function variants in PLD1 cause congenital right-sided cardiac valve defects and neonatal cardiomyopathy.
Lahrouchi N, Postma AV, Salazar CM, De Laughter DM, Tjong F, Piherová L, Bowling FZ, Zimmerman D, Lodder EM, Ta-Shma A, Perles Z, Beekman L, Ilgun A, Gunst Q, Hababa M, Škorić-Milosavljević D, Stránecký V, Tomek V, de Knijff P, de Leeuw R, Robinson JY, Burn SC, Mustafa H, Ambrose M, Moss T, Jacober J, Niyazov DM, Wolf B, Kim KH, Cherny S, Rousounides A, Aristidou-Kallika A, Tanteles G, Ange-Line B, Denommé-Pichon AS, Francannet C, Ortiz D, Haak MC, Ten Harkel AD, Manten GT, Dutman AC, Bouman K, Magliozzi M, Radio FC, Santen GW, Herkert JC, Brown HA, Elpeleg O, van den Hoff MJ, Mulder B, Airola MV, Kmoch S, Barnett JV, Clur SA, Frohman MA, Bezzina CR. Lahrouchi N, et al. Among authors: van den hoff mj. J Clin Invest. 2021 Mar 1;131(5):e142148. doi: 10.1172/JCI142148. J Clin Invest. 2021. PMID: 33645542 Free PMC article.
Cardiac regeneration from activated epicardium.
van Wijk B, Gunst QD, Moorman AF, van den Hoff MJ. van Wijk B, et al. Among authors: van den hoff mj. PLoS One. 2012;7(9):e44692. doi: 10.1371/journal.pone.0044692. Epub 2012 Sep 20. PLoS One. 2012. PMID: 23028582 Free PMC article.
Myocyte necrosis underlies progressive myocardial dystrophy in mouse dsg2-related arrhythmogenic right ventricular cardiomyopathy.
Pilichou K, Remme CA, Basso C, Campian ME, Rizzo S, Barnett P, Scicluna BP, Bauce B, van den Hoff MJ, de Bakker JM, Tan HL, Valente M, Nava A, Wilde AA, Moorman AF, Thiene G, Bezzina CR. Pilichou K, et al. Among authors: van den hoff mj. J Exp Med. 2009 Aug 3;206(8):1787-802. doi: 10.1084/jem.20090641. Epub 2009 Jul 27. J Exp Med. 2009. PMID: 19635863 Free PMC article.
The BMP antagonist follistatin-like 1 is required for skeletal and lung organogenesis.
Sylva M, Li VS, Buffing AA, van Es JH, van den Born M, van der Velden S, Gunst Q, Koolstra JH, Moorman AF, Clevers H, van den Hoff MJ. Sylva M, et al. Among authors: van der velden s, van den born m, van es jh, van den hoff mj. PLoS One. 2011;6(8):e22616. doi: 10.1371/journal.pone.0022616. Epub 2011 Aug 3. PLoS One. 2011. PMID: 21826198 Free PMC article.
Resveratrol Inhibits Aortic Root Dilatation in the Fbn1C1039G/+ Marfan Mouse Model.
Hibender S, Franken R, van Roomen C, Ter Braake A, van der Made I, Schermer EE, Gunst Q, van den Hoff MJ, Lutgens E, Pinto YM, Groenink M, Zwinderman AH, Mulder BJ, de Vries CJ, de Waard V. Hibender S, et al. Among authors: van der made i, van roomen c, van den hoff mj. Arterioscler Thromb Vasc Biol. 2016 Aug;36(8):1618-26. doi: 10.1161/ATVBAHA.116.307841. Epub 2016 Jun 9. Arterioscler Thromb Vasc Biol. 2016. PMID: 27283746 Free PMC article.
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