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Efficacy and safety of setmelanotide, an MC4R agonist, in individuals with severe obesity due to LEPR or POMC deficiency: single-arm, open-label, multicentre, phase 3 trials.
Clément K, van den Akker E, Argente J, Bahm A, Chung WK, Connors H, De Waele K, Farooqi IS, Gonneau-Lejeune J, Gordon G, Kohlsdorf K, Poitou C, Puder L, Swain J, Stewart M, Yuan G, Wabitsch M, Kühnen P; Setmelanotide POMC and LEPR Phase 3 Trial Investigators. Clément K, et al. Among authors: van den akker e. Lancet Diabetes Endocrinol. 2020 Dec;8(12):960-970. doi: 10.1016/S2213-8587(20)30364-8. Epub 2020 Oct 30. Lancet Diabetes Endocrinol. 2020. PMID: 33137293 Clinical Trial.
Leptin receptor deficiency: a systematic literature review and prevalence estimation based on population genetics.
Kleinendorst L, Abawi O, van der Kamp HJ, Alders M, Meijers-Heijboer HEJ, van Rossum EFC, van den Akker ELT, van Haelst MM. Kleinendorst L, et al. Among authors: van rossum efc, van haelst mm, van den akker elt, van der kamp hj. Eur J Endocrinol. 2020 Jan;182(1):47-56. doi: 10.1530/EJE-19-0678. Eur J Endocrinol. 2020. PMID: 31658438 Review.
Identifying underlying medical causes of pediatric obesity: Results of a systematic diagnostic approach in a pediatric obesity center.
Kleinendorst L, Abawi O, van der Voorn B, Jongejan MHTM, Brandsma AE, Visser JA, van Rossum EFC, van der Zwaag B, Alders M, Boon EMJ, van Haelst MM, van den Akker ELT. Kleinendorst L, et al. Among authors: van rossum efc, van haelst mm, van der zwaag b, van den akker elt, van der voorn b. PLoS One. 2020 May 8;15(5):e0232990. doi: 10.1371/journal.pone.0232990. eCollection 2020. PLoS One. 2020. PMID: 32384097 Free PMC article.
Clinical management of patients with genetic obesity during COVID-19 pandemic: position paper of the ESE Growth & Genetic Obesity COVID-19 Study Group and Rare Endo-ERN main thematic group on Growth and Obesity.
De Groot CJ, Poitou Bernert C, Coupaye M, Clement K, Paschou SA, Charmandari E, Kanaka-Gantenbein C, Wabitsch M, Buddingh EP, Nieuwenhuijsen B, Marina L, Johannsson G, Van Den Akker ELT. De Groot CJ, et al. Among authors: van den akker elt. Endocrine. 2021 Mar;71(3):653-662. doi: 10.1007/s12020-021-02619-y. Epub 2021 Jan 29. Endocrine. 2021. PMID: 33512658 Free PMC article. Review.
[Pharmacotherapy for obesity].
van Rossum EFC, Welling MS, van der Voorn B, van der Valk ES, Abawi O, van den Akker ELT. van Rossum EFC, et al. Among authors: van den akker elt, van der valk es, van der voorn b. Ned Tijdschr Geneeskd. 2021 Jan 19;165:D4907. Ned Tijdschr Geneeskd. 2021. PMID: 33560612 Dutch.
Impact of the COVID-19 Pandemic and Related Lockdown Measures on Lifestyle Behaviors and Well-Being in Children and Adolescents with Severe Obesity.
Welling MS, Abawi O, van den Eynde E, van Rossum EFC, Halberstadt J, Brandsma AE, Kleinendorst L, van den Akker ELT, van der Voorn B. Welling MS, et al. Among authors: van rossum efc, van den eynde e, van den akker elt, van der voorn b. Obes Facts. 2022;15(2):186-196. doi: 10.1159/000520718. Epub 2021 Nov 5. Obes Facts. 2022. PMID: 34743080 Free PMC article.
413 results