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Dysregulated RASGRP1 expression through RUNX1 mediated transcription promotes autoimmunity.
Baars MJD, Douma T, Simeonov DR, Myers DR, Kulhanek K, Banerjee S, Zwakenberg S, Baltissen MP, Amini M, de Roock S, van Wijk F, Vermeulen M, Marson A, Roose JP, Vercoulen Y. Baars MJD, et al. Among authors: van wijk f. Eur J Immunol. 2021 Feb;51(2):471-482. doi: 10.1002/eji.201948451. Epub 2020 Nov 16. Eur J Immunol. 2021. PMID: 33065764 Free PMC article.
Cord blood CD4+ T cells respond to self heat shock protein 60 (HSP60).
Aalberse JA, Kapitein B, de Roock S, Klein MR, de Jager W, van der Zee R, Hoekstra MO, van Wijk F, Prakken BJ. Aalberse JA, et al. Among authors: van der zee r, van wijk f. PLoS One. 2011;6(9):e24119. doi: 10.1371/journal.pone.0024119. Epub 2011 Sep 13. PLoS One. 2011. PMID: 21931651 Free PMC article.
Mesenchymal stem cell therapy in proteoglycan induced arthritis.
Swart JF, de Roock S, Hofhuis FM, Rozemuller H, van den Broek T, Moerer P, Broere F, van Wijk F, Kuis W, Prakken BJ, Martens AC, Wulffraat NM. Swart JF, et al. Among authors: van den broek t, van wijk f. Ann Rheum Dis. 2015 Apr;74(4):769-77. doi: 10.1136/annrheumdis-2013-204147. Epub 2014 Jan 6. Ann Rheum Dis. 2015. PMID: 24395558
Inhibition of Super-Enhancer Activity in Autoinflammatory Site-Derived T Cells Reduces Disease-Associated Gene Expression.
Peeters JG, Vervoort SJ, Tan SC, Mijnheer G, de Roock S, Vastert SJ, Nieuwenhuis EE, van Wijk F, Prakken BJ, Creyghton MP, Coffer PJ, Mokry M, van Loosdregt J. Peeters JG, et al. Among authors: van loosdregt j, van wijk f. Cell Rep. 2015 Sep 29;12(12):1986-96. doi: 10.1016/j.celrep.2015.08.046. Epub 2015 Sep 17. Cell Rep. 2015. PMID: 26387944 Free article.
Autoimmune disease-associated gene expression is reduced by BET-inhibition.
Peeters JG, Vervoort SJ, Mijnheer G, de Roock S, Vastert SJ, Nieuwenhuis EE, van Wijk F, Prakken BJ, Mokry M, van Loosdregt J. Peeters JG, et al. Among authors: van loosdregt j, van wijk f. Genom Data. 2015 Nov 7;7:14-7. doi: 10.1016/j.gdata.2015.11.004. eCollection 2016 Mar. Genom Data. 2015. PMID: 26981351 Free PMC article.
Human neonatal thymectomy induces altered B-cell responses and autoreactivity.
van den Broek T, Madi A, Delemarre EM, Schadenberg AWL, Tesselaar K, Borghans JAM, Nierkens S, Redegeld FA, Otten HG, Rossetti M, Albani S, Sorek R, Cohen IR, Jansen NJG, van Wijk F. van den Broek T, et al. Among authors: van wijk f. Eur J Immunol. 2017 Nov;47(11):1970-1981. doi: 10.1002/eji.201746971. Epub 2017 Sep 6. Eur J Immunol. 2017. PMID: 28691750 Free PMC article.
Antigen-driven PD-1+ TOX+ BHLHE40+ and PD-1+ TOX+ EOMES+ T lymphocytes regulate juvenile idiopathic arthritis in situ.
Maschmeyer P, Heinz GA, Skopnik CM, Lutter L, Mazzoni A, Heinrich F, von Stuckrad SL, Wirth LE, Tran CL, Riedel R, Lehmann K, Sakwa I, Cimaz R, Giudici F, Mall MA, Enghard P, Vastert B, Chang HD, Durek P, Annunziato F, van Wijk F, Radbruch A, Kallinich T, Mashreghi MF. Maschmeyer P, et al. Among authors: van wijk f. Eur J Immunol. 2021 Apr;51(4):915-929. doi: 10.1002/eji.202048797. Epub 2021 Feb 2. Eur J Immunol. 2021. PMID: 33296081 Free article.
Conserved human effector Treg cell transcriptomic and epigenetic signature in arthritic joint inflammation.
Mijnheer G, Lutter L, Mokry M, van der Wal M, Scholman R, Fleskens V, Pandit A, Tao W, Wekking M, Vervoort S, Roberts C, Petrelli A, Peeters JGC, Knijff M, de Roock S, Vastert S, Taams LS, van Loosdregt J, van Wijk F. Mijnheer G, et al. Among authors: van der wal m, van loosdregt j, van wijk f. Nat Commun. 2021 May 11;12(1):2710. doi: 10.1038/s41467-021-22975-7. Nat Commun. 2021. PMID: 33976194 Free PMC article.
Conjunctival inflammation in dupilumab-treated atopic dermatitis comprises a multicellular infiltrate with elevated T1/T17 cytokines: A case series study.
Bakker DS, Ter Linde JJM, Amini MM, Ariëns LFM, van Luijk CM, de Bruin-Weller MS, Thijs JL, Vercoulen Y, van Wijk F. Bakker DS, et al. Among authors: van luijk cm, van wijk f. Allergy. 2021 Dec;76(12):3814-3817. doi: 10.1111/all.15064. Epub 2021 Sep 4. Allergy. 2021. PMID: 34449906 Free PMC article. No abstract available.
148 results