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Anti-LRP5/6 VHHs promote differentiation of Wnt-hypersensitive intestinal stem cells.
Fenderico N, van Scherpenzeel RC, Goldflam M, Proverbio D, Jordens I, Kralj T, Stryeck S, Bass TZ, Hermans G, Ullman C, Aastrup T, Gros P, Maurice MM. Fenderico N, et al. Among authors: van scherpenzeel rc. Nat Commun. 2019 Jan 21;10(1):365. doi: 10.1038/s41467-018-08172-z. Nat Commun. 2019. PMID: 30664649 Free PMC article.
Axin cancer mutants form nanoaggregates to rewire the Wnt signaling network.
Anvarian Z, Nojima H, van Kappel EC, Madl T, Spit M, Viertler M, Jordens I, Low TY, van Scherpenzeel RC, Kuper I, Richter K, Heck AJ, Boelens R, Vincent JP, Rüdiger SG, Maurice MM. Anvarian Z, et al. Among authors: van scherpenzeel rc. Nat Struct Mol Biol. 2016 Apr;23(4):324-32. doi: 10.1038/nsmb.3191. Epub 2016 Mar 14. Nat Struct Mol Biol. 2016. PMID: 26974125