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Validating TDP1 as an Inhibition Target for the Development of Chemosensitizers for Camptothecin-Based Chemotherapy Drugs.
Leung E, Patel J, Hollywood JA, Zafar A, Tomek P, Barker D, Pilkington LI, van Rensburg M, Langley RJ, Helsby NA, Squire CJ, Baguley BC, Denny WA, Reynisson J, Leung IKH. Leung E, et al. Among authors: van rensburg m. Oncol Ther. 2021 Dec;9(2):541-556. doi: 10.1007/s40487-021-00158-0. Epub 2021 Jun 23. Oncol Ther. 2021. PMID: 34159519 Free PMC article.
Thieno[2,3-b]pyridine derivatives are potent anti-platelet drugs, inhibiting platelet activation, aggregation and showing synergy with aspirin.
Binsaleh NK, Wigley CA, Whitehead KA, van Rensburg M, Reynisson J, Pilkington LI, Barker D, Jones S, Dempsey-Hibbert NC. Binsaleh NK, et al. Among authors: van rensburg m. Eur J Med Chem. 2018 Jan 1;143:1997-2004. doi: 10.1016/j.ejmech.2017.11.014. Epub 2017 Nov 7. Eur J Med Chem. 2018. PMID: 29129512 Free article.
GPCR Modulation of Thieno[2,3-b]pyridine Anti-Proliferative Agents.
Zafar A, Sari S, Leung E, Pilkington LI, van Rensburg M, Barker D, Reynisson J. Zafar A, et al. Among authors: van rensburg m. Molecules. 2017 Dec 18;22(12):2254. doi: 10.3390/molecules22122254. Molecules. 2017. PMID: 29258235 Free PMC article.
55 results