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Biological and structural characterization of murine TRALI antibody reveals increased Fc-mediated complement activation.
Zeeuw van der Laan EAN, van der Velden S, Bentlage AEH, Larsen MD, van Osch TLJ, Mok JY, Brasser G, Geerdes DM, Koeleman CAM, Nouta J, Semple JW, Porcelijn L, van Esch WJE, Wuhrer M, van der Schoot CE, Vidarsson G, Kapur R. Zeeuw van der Laan EAN, et al. Among authors: van osch tlj. Blood Adv. 2020 Aug 25;4(16):3875-3885. doi: 10.1182/bloodadvances.2020002291. Blood Adv. 2020. PMID: 32810222 Free PMC article.
Fc galactosylation of anti-platelet human IgG1 alloantibodies enhances complement activation on platelets.
Van Osch TLJ, Oosterhoff JJ, Bentlage AEH, Nouta J, Koeleman CAM, Geerdes DM, Mok JY, Heidt S, Mulder A, Van Esch WJE, Kapur R, Porcelijn L, Van der Schoot CE, De Haas M, Wuhrer M, Voorberg J, Vidarsson G. Van Osch TLJ, et al. Haematologica. 2022 Oct 1;107(10):2432-2444. doi: 10.3324/haematol.2021.280493. Haematologica. 2022. PMID: 35354253 Free PMC article.
Altered Fc glycosylation of anti-HLA alloantibodies in hemato-oncological patients receiving platelet transfusions.
van Osch TLJ, Pongracz T, Geerdes DM, Mok JY, van Esch WJE, Voorberg J, Kapur R, Porcelijn L, Kerkhoffs JH, van der Meer PF, van der Schoot CE, de Haas M, Wuhrer M, Vidarsson G. van Osch TLJ, et al. J Thromb Haemost. 2022 Dec;20(12):3011-3025. doi: 10.1111/jth.15898. Epub 2022 Oct 11. J Thromb Haemost. 2022. PMID: 36165642 Free PMC article.
Complement activation drives antibody-mediated transfusion-related acute lung injury via macrophage trafficking and formation of NETs.
van der Velden S, van Osch TLJ, Seghier A, Bentlage AEH, Mok JY, Geerdes DM, van Esch WJE, Pouw RB, Brouwer MC, Jongerius I, de Haas M, Porcelijn L, van der Schoot CE, Vidarsson G, Kapur R. van der Velden S, et al. Among authors: van osch tlj. Blood. 2024 Jan 4;143(1):79-91. doi: 10.1182/blood.2023020484. Blood. 2024. PMID: 37801721
Imaging the ocular motor nerves.
Ferreira T, Verbist B, van Buchem M, van Osch T, Webb A. Ferreira T, et al. Eur J Radiol. 2010 May;74(2):314-22. doi: 10.1016/j.ejrad.2009.05.066. Epub 2010 Mar 11. Eur J Radiol. 2010. PMID: 20226610
Impact of structural modifications of IgG antibodies on effector functions.
Damelang T, Brinkhaus M, van Osch TLJ, Schuurman J, Labrijn AF, Rispens T, Vidarsson G. Damelang T, et al. Among authors: van osch tlj. Front Immunol. 2024 Jan 8;14:1304365. doi: 10.3389/fimmu.2023.1304365. eCollection 2023. Front Immunol. 2024. PMID: 38259472 Free PMC article. Review.
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