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Safety and efficacy of mitapivat, an oral pyruvate kinase activator, in sickle cell disease: A phase 2, open-label study.
van Dijk MJ, Rab MAE, van Oirschot BA, Bos J, Derichs C, Rijneveld AW, Cnossen MH, Nur E, Biemond BJ, Bartels M, Jans JJM, van Solinge WW, Schutgens REG, van Wijk R, van Beers EJ. van Dijk MJ, et al. Among authors: van oirschot ba, van wijk r, van solinge ww, van beers ej. Am J Hematol. 2022 Jul;97(7):E226-E229. doi: 10.1002/ajh.26554. Epub 2022 Apr 16. Am J Hematol. 2022. PMID: 35384026 Free article. Clinical Trial. No abstract available.
Taxol(®)-induced phosphatidylserine exposure and microvesicle formation in red blood cells is mediated by its vehicle Cremophor(®) EL.
Vader P, Fens MH, Sachini N, van Oirschot BA, Andringa G, Egberts AC, Gaillard CA, Rasmussen JT, van Wijk R, van Solinge WW, Schiffelers RM. Vader P, et al. Among authors: van oirschot ba, van wijk r, van solinge ww. Nanomedicine (Lond). 2013 Jul;8(7):1127-35. doi: 10.2217/nnm.12.163. Epub 2013 Feb 5. Nanomedicine (Lond). 2013. PMID: 23384701
Ribosomal protein mutations induce autophagy through S6 kinase inhibition of the insulin pathway.
Heijnen HF, van Wijk R, Pereboom TC, Goos YJ, Seinen CW, van Oirschot BA, van Dooren R, Gastou M, Giles RH, van Solinge W, Kuijpers TW, Gazda HT, Bierings MB, Da Costa L, MacInnes AW. Heijnen HF, et al. Among authors: van oirschot ba, van wijk r, van dooren r, van solinge w. PLoS Genet. 2014 May 29;10(5):e1004371. doi: 10.1371/journal.pgen.1004371. eCollection 2014. PLoS Genet. 2014. PMID: 24875531 Free PMC article.
Novel Homozygous Mutation of the Internal Translation Initiation Start Site of VHL is Exclusively Associated with Erythrocytosis: Indications for Distinct Functional Roles of von Hippel-Lindau Tumor Suppressor Isoforms.
Bartels M, van der Zalm MM, van Oirschot BA, Lee FS, Giles RH, Kruip MJ, Gitz-Francois JJ, Van Solinge WW, Bierings M, van Wijk R. Bartels M, et al. Among authors: van der zalm mm, van oirschot ba, van wijk r, van solinge ww. Hum Mutat. 2015 Nov;36(11):1039-42. doi: 10.1002/humu.22846. Epub 2015 Aug 17. Hum Mutat. 2015. PMID: 26224408
67 results