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Negative regulation of the NLRP3 inflammasome by A20 protects against arthritis.
Vande Walle L, Van Opdenbosch N, Jacques P, Fossoul A, Verheugen E, Vogel P, Beyaert R, Elewaut D, Kanneganti TD, van Loo G, Lamkanfi M. Vande Walle L, et al. Among authors: van opdenbosch n, van loo g. Nature. 2014 Aug 7;512(7512):69-73. doi: 10.1038/nature13322. Epub 2014 Jun 29. Nature. 2014. PMID: 25043000 Free PMC article.
A20 controls intestinal homeostasis through cell-specific activities.
Vereecke L, Vieira-Silva S, Billiet T, van Es JH, Mc Guire C, Slowicka K, Sze M, van den Born M, De Hertogh G, Clevers H, Raes J, Rutgeerts P, Vermeire S, Beyaert R, van Loo G. Vereecke L, et al. Among authors: van den born m, van es jh, van loo g. Nat Commun. 2014 Sep 30;5:5103. doi: 10.1038/ncomms6103. Nat Commun. 2014. PMID: 25267258 Free article.
Identification of Immune-Responsive Gene 1 (IRG1) as a Target of A20.
Van Quickelberghe E, Martens A, Goeminne LJE, Clement L, van Loo G, Gevaert K. Van Quickelberghe E, et al. Among authors: van loo g. J Proteome Res. 2018 Jun 1;17(6):2182-2191. doi: 10.1021/acs.jproteome.8b00139. Epub 2018 May 11. J Proteome Res. 2018. PMID: 29733654
A20 critically controls microglia activation and inhibits inflammasome-dependent neuroinflammation.
Voet S, Mc Guire C, Hagemeyer N, Martens A, Schroeder A, Wieghofer P, Daems C, Staszewski O, Vande Walle L, Jordao MJC, Sze M, Vikkula HK, Demeestere D, Van Imschoot G, Scott CL, Hoste E, Gonçalves A, Guilliams M, Lippens S, Libert C, Vandenbroucke RE, Kim KW, Jung S, Callaerts-Vegh Z, Callaerts P, de Wit J, Lamkanfi M, Prinz M, van Loo G. Voet S, et al. Among authors: van imschoot g, van loo g. Nat Commun. 2018 May 23;9(1):2036. doi: 10.1038/s41467-018-04376-5. Nat Commun. 2018. PMID: 29789522 Free PMC article.
Physical and functional interaction between A20 and ATG16L1-WD40 domain in the control of intestinal homeostasis.
Slowicka K, Serramito-Gómez I, Boada-Romero E, Martens A, Sze M, Petta I, Vikkula HK, De Rycke R, Parthoens E, Lippens S, Savvides SN, Wullaert A, Vereecke L, Pimentel-Muiños FX, van Loo G. Slowicka K, et al. Among authors: van loo g. Nat Commun. 2019 Apr 23;10(1):1834. doi: 10.1038/s41467-019-09667-z. Nat Commun. 2019. PMID: 31015422 Free PMC article.
A20 phosphorylation controls A20 function.
Martens A, van Loo G. Martens A, et al. Among authors: van loo g. Nat Immunol. 2019 Oct;20(10):1261-1262. doi: 10.1038/s41590-019-0481-3. Nat Immunol. 2019. PMID: 31534239 No abstract available.
156 results