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Nuclear Receptor Nur77 Limits the Macrophage Inflammatory Response through Transcriptional Reprogramming of Mitochondrial Metabolism.
Koenis DS, Medzikovic L, van Loenen PB, van Weeghel M, Huveneers S, Vos M, Evers-van Gogh IJ, Van den Bossche J, Speijer D, Kim Y, Wessels L, Zelcer N, Zwart W, Kalkhoven E, de Vries CJ. Koenis DS, et al. Among authors: van loenen pb. Cell Rep. 2018 Aug 21;24(8):2127-2140.e7. doi: 10.1016/j.celrep.2018.07.065. Cell Rep. 2018. PMID: 30134173 Free PMC article.
Nur77 variants solely comprising the amino-terminal domain activate hypoxia-inducible factor-1α and affect bone marrow homeostasis in mice and humans.
Koenis DS, Medzikovic L, Vos M, Beldman TJ, van Loenen PB, van Tiel CM, Hamers AAJ, Otermin Rubio I, de Waard V, de Vries CJM. Koenis DS, et al. Among authors: van loenen pb. J Biol Chem. 2018 Sep 28;293(39):15070-15083. doi: 10.1074/jbc.RA118.002720. Epub 2018 Aug 15. J Biol Chem. 2018. PMID: 30111591 Free PMC article.
Structural and cellular mechanisms of peptidyl-prolyl isomerase Pin1-mediated enhancement of Tissue Factor gene expression, protein half-life, and pro-coagulant activity.
Kurakula K, Koenis DS, Herzik MA Jr, Liu Y, Craft JW Jr, van Loenen PB, Vos M, Tran MK, Versteeg HH, Goumans MTH, Ruf W, de Vries CJM, Şen M. Kurakula K, et al. Among authors: van loenen pb. Haematologica. 2018 Jun;103(6):1073-1082. doi: 10.3324/haematol.2017.183087. Epub 2018 Mar 15. Haematologica. 2018. PMID: 29545340 Free PMC article.
Sphingosine-1-Phosphate Receptor 1 Regulates Cardiac Function by Modulating Ca2+ Sensitivity and Na+/H+ Exchange and Mediates Protection by Ischemic Preconditioning.
Keul P, van Borren MM, Ghanem A, Müller FU, Baartscheer A, Verkerk AO, Stümpel F, Schulte JS, Hamdani N, Linke WA, van Loenen P, Matus M, Schmitz W, Stypmann J, Tiemann K, Ravesloot JH, Alewijnse AE, Hermann S, Spijkers LJ, Hiller KH, Herr D, Heusch G, Schäfers M, Peters SL, Chun J, Levkau B. Keul P, et al. J Am Heart Assoc. 2016 May 20;5(5):e003393. doi: 10.1161/JAHA.116.003393. J Am Heart Assoc. 2016. PMID: 27207969 Free PMC article.
16 results