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The neo-open reading frame peptides that comprise the tumor framome are a rich source of neoantigens for cancer immunotherapy.
Martin MV, Aguilar-Rosas S, Franke K, Pieterse M, van Langelaar J, Schreurs RR, Bijlsma MF, Besselink MG, Koster J, Timens W, Khasraw M, Ashley DM, Keir ST, Ottensmeier CH, King EV, Verheij J, Waasdorp C, Valk PJM, Engels SA, Oostenbach E, van Dinter JT, Hofman DA, Mok JY, van Esch WJE, Wilmink H, Monkhorst K, Verheul HMW, Poel D, Hiltermann TJN, van Kempen LC, Groen HJ, Aerts JGJV, van Heesch S, Lowenberg B, Plasterk R, Kloosterman WP. Martin MV, et al. Among authors: van langelaar j. Cancer Immunol Res. 2024 Apr 4. doi: 10.1158/2326-6066.CIR-23-0158. Online ahead of print. Cancer Immunol Res. 2024. PMID: 38573707
Selective emergence of antibody-secreting cells in the multiple sclerosis brain.
Bogers L, Engelenburg HJ, Janssen M, Unger PA, Melief MJ, Wierenga-Wolf AF, Hsiao CC, Mason MRJ, Hamann J, van Langelaar J, Smolders J, van Luijn MM. Bogers L, et al. Among authors: van langelaar j. EBioMedicine. 2023 Mar;89:104465. doi: 10.1016/j.ebiom.2023.104465. Epub 2023 Feb 14. EBioMedicine. 2023. PMID: 36796230 Free PMC article.
Human T-bet+ B cell development is associated with BTK activity and suppressed by evobrutinib.
Rijvers L, van Langelaar J, Bogers L, Melief MJ, Koetzier SC, Blok KM, Wierenga-Wolf AF, de Vries HE, Rip J, Corneth OB, Hendriks RW, Grenningloh R, Boschert U, Smolders J, van Luijn MM. Rijvers L, et al. Among authors: van langelaar j. JCI Insight. 2022 Aug 22;7(16):e160909. doi: 10.1172/jci.insight.160909. JCI Insight. 2022. PMID: 35852869 Free PMC article.
Distinct Effector Programs of Brain-Homing CD8+ T Cells in Multiple Sclerosis.
Koetzier SC, van Langelaar J, Melief MJ, Wierenga-Wolf AF, Corsten CEA, Blok KM, Hoeks C, Broux B, Wokke B, van Luijn MM, Smolders J. Koetzier SC, et al. Among authors: van langelaar j. Cells. 2022 May 13;11(10):1634. doi: 10.3390/cells11101634. Cells. 2022. PMID: 35626671 Free PMC article.
Pregnancy-induced effects on memory B-cell development in multiple sclerosis.
Janssen M, Rijvers L, Koetzier SC, Wierenga-Wolf AF, Melief MJ, van Langelaar J, Runia TF, de Groot CJM, Neuteboom R, Smolders J, van Luijn MM. Janssen M, et al. Among authors: van langelaar j. Sci Rep. 2021 Jun 9;11(1):12126. doi: 10.1038/s41598-021-91655-9. Sci Rep. 2021. PMID: 34108575 Free PMC article.
Brain-homing CD4+ T cells display glucocorticoid-resistant features in MS.
Koetzier SC, van Langelaar J, Blok KM, van den Bosch TPP, Wierenga-Wolf AF, Melief MJ, Pol K, Siepman TA, Verjans GMGM, Smolders J, Lubberts E, de Vries HE, van Luijn MM. Koetzier SC, et al. Among authors: van langelaar j. Neurol Neuroimmunol Neuroinflamm. 2020 Oct 9;7(6):e894. doi: 10.1212/NXI.0000000000000894. Print 2020 Nov. Neurol Neuroimmunol Neuroinflamm. 2020. PMID: 33037101 Free PMC article.
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