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Spatial transcriptomics unveils ZBTB11 as a regulator of cardiomyocyte degeneration in arrhythmogenic cardiomyopathy.
Boogerd CJ, Lacraz GPA, Vértesy Á, van Kampen SJ, Perini I, de Ruiter H, Versteeg D, Brodehl A, van der Kraak P, Giacca M, de Jonge N, Junker JP, van Oudenaarden A, Vink A, van Rooij E. Boogerd CJ, et al. Among authors: van kampen sj. Cardiovasc Res. 2023 Mar 31;119(2):477-491. doi: 10.1093/cvr/cvac072. Cardiovasc Res. 2023. PMID: 35576477 Free PMC article.
Epicardial differentiation drives fibro-fatty remodeling in arrhythmogenic cardiomyopathy.
Kohela A, van Kampen SJ, Moens T, Wehrens M, Molenaar B, Boogerd CJ, Monshouwer-Kloots J, Perini I, Goumans MJ, Smits AM, van Tintelen JP, van Rooij E. Kohela A, et al. Among authors: van kampen sj. Sci Transl Med. 2021 Sep 22;13(612):eabf2750. doi: 10.1126/scitranslmed.abf2750. Epub 2021 Sep 22. Sci Transl Med. 2021. PMID: 34550725
CRISPR Craze to Transform Cardiac Biology.
van Kampen SJ, van Rooij E. van Kampen SJ, et al. Trends Mol Med. 2019 Sep;25(9):791-802. doi: 10.1016/j.molmed.2019.06.008. Epub 2019 Jul 17. Trends Mol Med. 2019. PMID: 31326354 Free article. Review.
CRISPR base editing lowers cholesterol in monkeys.
van Kampen SJ, van Rooij E. van Kampen SJ, et al. Nat Biotechnol. 2021 Aug;39(8):920-921. doi: 10.1038/s41587-021-00975-8. Nat Biotechnol. 2021. PMID: 34168346 No abstract available.
Desmosomal protein degradation as an underlying cause of arrhythmogenic cardiomyopathy.
Tsui H, van Kampen SJ, Han SJ, Meraviglia V, van Ham WB, Casini S, van der Kraak P, Vink A, Yin X, Mayr M, Bossu A, Marchal GA, Monshouwer-Kloots J, Eding J, Versteeg D, de Ruiter H, Bezstarosti K, Groeneweg J, Klaasen SJ, van Laake LW, Demmers JAA, Kops GJPL, Mummery CL, van Veen TAB, Remme CA, Bellin M, van Rooij E. Tsui H, et al. Among authors: van kampen sj. Sci Transl Med. 2023 Mar 22;15(688):eadd4248. doi: 10.1126/scitranslmed.add4248. Epub 2023 Mar 22. Sci Transl Med. 2023. PMID: 36947592
PITX2 induction leads to impaired cardiomyocyte function in arrhythmogenic cardiomyopathy.
van Kampen SJ, Han SJ, van Ham WB, Kyriakopoulou E, Stouthart EW, Goversen B, Monshouwer-Kloots J, Perini I, de Ruiter H, van der Kraak P, Vink A, van Laake LW, Groeneweg JA, de Boer TP, Tsui H, Boogerd CJ, van Veen TAB, van Rooij E. van Kampen SJ, et al. Stem Cell Reports. 2023 Mar 14;18(3):749-764. doi: 10.1016/j.stemcr.2023.01.015. Epub 2023 Mar 2. Stem Cell Reports. 2023. PMID: 36868229 Free PMC article.
Therapeutic efficacy of AAV-mediated restoration of PKP2 in arrhythmogenic cardiomyopathy.
Kyriakopoulou E, Versteeg D, de Ruiter H, Perini I, Seibertz F, Döring Y, Zentilin L, Tsui H, van Kampen SJ, Tiburcy M, Meyer T, Voigt N, Tintelen VJP, Zimmermann WH, Giacca M, van Rooij E. Kyriakopoulou E, et al. Among authors: van kampen sj. Nat Cardiovasc Res. 2023;2(12):1262-1276. doi: 10.1038/s44161-023-00378-9. Epub 2023 Dec 7. Nat Cardiovasc Res. 2023. PMID: 38665939 Free PMC article.