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The selective orexin-2 antagonist seltorexant (JNJ-42847922/MIN-202) shows antidepressant and sleep-promoting effects in patients with major depressive disorder.
Recourt K, de Boer P, Zuiker R, Luthringer R, Kent J, van der Ark P, Van Hove I, van Gerven J, Jacobs G, van Nueten L, Drevets W. Recourt K, et al. Among authors: van hove i, van nueten l, van der ark p, van gerven j. Transl Psychiatry. 2019 Sep 3;9(1):216. doi: 10.1038/s41398-019-0553-z. Transl Psychiatry. 2019. PMID: 31481683 Free PMC article. Clinical Trial.
Pharmacology of rising oral doses of 5-hydroxytryptophan with carbidopa.
Smarius LJ, Jacobs GE, Hoeberechts-Lefrandt DH, de Kam ML, van der Post JP, de Rijk R, van Pelt J, Schoemaker RC, Zitman FG, van Gerven JM, Gijsman HJ. Smarius LJ, et al. Among authors: van gerven jm, van der post jp, van pelt j. J Psychopharmacol. 2008 Jun;22(4):426-33. doi: 10.1177/0269881107082025. Epub 2008 Feb 28. J Psychopharmacol. 2008. PMID: 18308795 Clinical Trial.
The effects of a glycine reuptake inhibitor R231857 on the central nervous system and on scopolamine-induced impairments in cognitive and psychomotor function in healthy subjects.
Liem-Moolenaar M, Zoethout RW, de Boer P, Schmidt M, de Kam ML, Cohen AF, Franson KL, van Gerven JM. Liem-Moolenaar M, et al. Among authors: van gerven jm. J Psychopharmacol. 2010 Nov;24(11):1681-7. doi: 10.1177/0269881109105573. Epub 2009 Jul 31. J Psychopharmacol. 2010. PMID: 19648218 Clinical Trial.
Hypothalamic glutamate levels following serotonergic stimulation: a pilot study using 7-Tesla magnetic resonance spectroscopy in healthy volunteers.
Jacobs GE, der Grond Jv, Teeuwisse WM, Langeveld TJ, van Pelt J, Verhagen JC, de Kam ML, Cohen AF, Zitman FG, van Gerven JM. Jacobs GE, et al. Among authors: van gerven jm, van pelt j. Prog Neuropsychopharmacol Biol Psychiatry. 2010 Apr 16;34(3):486-91. doi: 10.1016/j.pnpbp.2010.01.019. Epub 2010 Feb 4. Prog Neuropsychopharmacol Biol Psychiatry. 2010. PMID: 20138102 Clinical Trial.
Desmopressin as a pharmacological tool in vasopressinergic hypothalamus-pituitary-adrenal axis modulation: neuroendocrine, cardiovascular and coagulatory effects.
Jacobs GE, Hulskotte EG, van Gerven JM, Zuurman L, de Kam ML, Elassaiss-Schaap J, Ruigt G, van Pelt J, Peeters BW, Peeters PA, Burggraaf J. Jacobs GE, et al. Among authors: van gerven jm, van pelt j. J Psychopharmacol. 2011 Mar;25(3):353-60. doi: 10.1177/0269881109358203. Epub 2010 Feb 8. J Psychopharmacol. 2011. PMID: 20142306 Clinical Trial.
The effects of the glycine reuptake inhibitor R213129 on the central nervous system and on scopolamine-induced impairments in psychomotor and cognitive function in healthy subjects.
Liem-Moolenaar M, Zoethout RW, de Boer P, Schmidt M, de Kam ML, Cohen AF, Franson KL, van Gerven JM. Liem-Moolenaar M, et al. Among authors: van gerven jm. J Psychopharmacol. 2010 Nov;24(11):1671-9. doi: 10.1177/0269881109106942. Epub 2010 Feb 8. J Psychopharmacol. 2010. PMID: 20142308 Clinical Trial.
A pharmacological tool to assess vasopressinergic co-activation of the hypothalamus-pituitary-adrenal axis more integrally in healthy volunteers.
Jacobs GE, van Gerven JM, de Kam Ml, Elassaiss-Schaap J, Ruigt G, van Pelt J, Peeters BW, Peeters PA, Hulskotte EG. Jacobs GE, et al. Among authors: van gerven jm, van pelt j. J Psychopharmacol. 2011 Mar;25(3):361-9. doi: 10.1177/0269881109358205. Epub 2010 Feb 10. J Psychopharmacol. 2011. PMID: 20147570 Clinical Trial.
Metoclopramide as pharmacological tool to assess vasopressinergic co-activation of the hypothalamus-pituitary-adrenal (HPA) axis: a study in healthy volunteers.
Jacobs GE, Hulskotte EG, de Kam ML, Zha G, Jiang J, Hu P, Zhao Q, van Pelt J, Goekoop JG, Zitman FG, van Gerven JM. Jacobs GE, et al. Among authors: van gerven jm, van pelt j. Eur Neuropsychopharmacol. 2010 Dec;20(12):866-74. doi: 10.1016/j.euroneuro.2010.06.009. Epub 2010 Jul 23. Eur Neuropsychopharmacol. 2010. PMID: 20655180 Clinical Trial.
218 results