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Discovery of Selective Nanomolar Inhibitors for Insulin-Regulated Aminopeptidase Based on α-Hydroxy-β-amino Acid Derivatives of Bestatin.
Vourloumis D, Mavridis I, Athanasoulis A, Temponeras I, Koumantou D, Giastas P, Mpakali A, Magrioti V, Leib J, van Endert P, Stratikos E, Papakyriakou A. Vourloumis D, et al. Among authors: van endert p. J Med Chem. 2022 Jul 28;65(14):10098-10117. doi: 10.1021/acs.jmedchem.2c00904. Epub 2022 Jul 14. J Med Chem. 2022. PMID: 35833347
Optimization and Structure-Activity Relationships of Phosphinic Pseudotripeptide Inhibitors of Aminopeptidases That Generate Antigenic Peptides.
Kokkala P, Mpakali A, Mauvais FX, Papakyriakou A, Daskalaki I, Petropoulou I, Kavvalou S, Papathanasopoulou M, Agrotis S, Fonsou TM, van Endert P, Stratikos E, Georgiadis D. Kokkala P, et al. Among authors: van endert p. J Med Chem. 2016 Oct 13;59(19):9107-9123. doi: 10.1021/acs.jmedchem.6b01031. Epub 2016 Sep 20. J Med Chem. 2016. PMID: 27606717
IRAP-dependent endosomal T cell receptor signalling is essential for T cell responses.
Evnouchidou I, Chappert P, Benadda S, Zucchetti A, Weimershaus M, Bens M, Caillens V, Koumantou D, Lotersztajn S, van Endert P, Davoust J, Guermonprez P, Hivroz C, Gross DA, Saveanu L. Evnouchidou I, et al. Among authors: van endert p. Nat Commun. 2020 Jun 2;11(1):2779. doi: 10.1038/s41467-020-16471-7. Nat Commun. 2020. PMID: 32487999 Free PMC article.
Trimming of MHC Class I Ligands by ERAP Aminopeptidases.
Weimershaus M, Evnouchidou I, Li L, van Endert P, Bouvier M. Weimershaus M, et al. Among authors: van endert p. Methods Mol Biol. 2019;1988:31-43. doi: 10.1007/978-1-4939-9450-2_3. Methods Mol Biol. 2019. PMID: 31147930 Free PMC article.
178 results