van Delft JH - Search Results

1

Concentration-dependent gene expression responses to flusilazole in embryonic stem cell differentiation cultures.

van Dartel DA, Pennings JL, de la Fonteyne LJ, Brauers KJ, Claessen S, van Delft JH, Kleinjans JC, Piersma AH. van Dartel DA, et al. Among authors: van delft jh. Toxicol Appl Pharmacol. 2011 Mar 1;251(2):110-8. doi: 10.1016/j.taap.2010.12.008. Epub 2010 Dec 28. Toxicol Appl Pharmacol. 2011. PMID: 21192963

2

Monitoring developmental toxicity in the embryonic stem cell test using differential gene expression of differentiation-related genes.

van Dartel DA, Pennings JL, de la Fonteyne LJ, van Herwijnen MH, van Delft JH, van Schooten FJ, Piersma AH. van Dartel DA, et al. Among authors: van herwijnen mh, van schooten fj, van delft jh. Toxicol Sci. 2010 Jul;116(1):130-9. doi: 10.1093/toxsci/kfq127. Epub 2010 Apr 26. Toxicol Sci. 2010. PMID: 20421339

3

Evaluation of developmental toxicant identification using gene expression profiling in embryonic stem cell differentiation cultures.

van Dartel DA, Pennings JL, de la Fonteyne LJ, Brauers KJ, Claessen S, van Delft JH, Kleinjans JC, Piersma AH. van Dartel DA, et al. Among authors: van delft jh. Toxicol Sci. 2011 Jan;119(1):126-34. doi: 10.1093/toxsci/kfq291. Epub 2010 Oct 8. Toxicol Sci. 2011. PMID: 20935163

4

Deregulation of cancer-related pathways in primary hepatocytes derived from DNA repair-deficient Xpa-/-p53+/- mice upon exposure to benzo[a]pyrene.

van Kesteren PC, Zwart PE, Pennings JL, Gottschalk WH, Kleinjans JC, van Delft JH, van Steeg H, Luijten M. van Kesteren PC, et al. Among authors: van steeg h, van delft jh. Toxicol Sci. 2011 Sep;123(1):123-32. doi: 10.1093/toxsci/kfr169. Epub 2011 Jun 29. Toxicol Sci. 2011. PMID: 21715664

5

Application of toxicogenomics in hepatic systems toxicology for risk assessment: acetaminophen as a case study.

Kienhuis AS, Bessems JG, Pennings JL, Driessen M, Luijten M, van Delft JH, Peijnenburg AA, van der Ven LT. Kienhuis AS, et al. Among authors: van der ven lt, van delft jh. Toxicol Appl Pharmacol. 2011 Jan 15;250(2):96-107. doi: 10.1016/j.taap.2010.10.013. Epub 2010 Oct 21. Toxicol Appl Pharmacol. 2011. PMID: 20970440 Review.

6

Omics-based identification of the combined effects of idiosyncratic drugs and inflammatory cytokines on the development of drug-induced liver injury.

Jiang J, Mathijs K, Timmermans L, Claessen SM, Hecka A, Weusten J, Peters R, van Delft JH, Kleinjans JCS, Jennen DGJ, de Kok TM. Jiang J, et al. Among authors: van delft jh. Toxicol Appl Pharmacol. 2017 Oct 1;332:100-108. doi: 10.1016/j.taap.2017.07.014. Epub 2017 Jul 18. Toxicol Appl Pharmacol. 2017. PMID: 28733206

7

A toxicogenomics-based parallelogram approach to evaluate the relevance of coumarin-induced responses in primary human hepatocytes in vitro for humans in vivo.

Kienhuis AS, van de Poll MC, Dejong CH, Gottschalk R, van Herwijnen M, Boorsma A, Kleinjans JC, Stierum RH, van Delft JH. Kienhuis AS, et al. Among authors: van herwijnen m, van de poll mc, van delft jh. Toxicol In Vitro. 2009 Sep;23(6):1163-9. doi: 10.1016/j.tiv.2009.06.005. Epub 2009 Jun 13. Toxicol In Vitro. 2009. PMID: 19527782

8

Discrimination for genotoxic and nongenotoxic carcinogens by gene expression profiling in primary mouse hepatocytes improves with exposure time.

Mathijs K, Brauers KJ, Jennen DG, Boorsma A, van Herwijnen MH, Gottschalk RW, Kleinjans JC, van Delft JH. Mathijs K, et al. Among authors: van herwijnen mh, van delft jh. Toxicol Sci. 2009 Dec;112(2):374-84. doi: 10.1093/toxsci/kfp229. Epub 2009 Sep 21. Toxicol Sci. 2009. PMID: 19770486

9

Time series analysis of benzo[A]pyrene-induced transcriptome changes suggests that a network of transcription factors regulates the effects on functional gene sets.

van Delft JH, Mathijs K, Staal YC, van Herwijnen MH, Brauers KJ, Boorsma A, Kleinjans JC. van Delft JH, et al. Among authors: van herwijnen mh. Toxicol Sci. 2010 Oct;117(2):381-92. doi: 10.1093/toxsci/kfq214. Epub 2010 Jul 12. Toxicol Sci. 2010. PMID: 20624995

10

'Omics analysis of low dose acetaminophen intake demonstrates novel response pathways in humans.

Jetten MJ, Gaj S, Ruiz-Aracama A, de Kok TM, van Delft JH, Lommen A, van Someren EP, Jennen DG, Claessen SM, Peijnenburg AA, Stierum RH, Kleinjans JC. Jetten MJ, et al. Among authors: van someren ep, van delft jh. Toxicol Appl Pharmacol. 2012 Mar 15;259(3):320-8. doi: 10.1016/j.taap.2012.01.009. Epub 2012 Jan 20. Toxicol Appl Pharmacol. 2012. PMID: 22285215 Clinical Trial.

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