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Page 1
IgM N-glycosylation correlates with COVID-19 severity and rate of complement deposition.
Haslund-Gourley BS, Woloszczuk K, Hou J, Connors J, Cusimano G, Bell M, Taramangalam B, Fourati S, Mege N, Bernui M, Altman MC, Krammer F, van Bakel H; IMPACC Network; Maecker HT, Rouphael N, Diray-Arce J, Wigdahl B, Kutzler MA, Cairns CB, Haddad EK, Comunale MA. Haslund-Gourley BS, et al. Among authors: van bakel h. Nat Commun. 2024 Jan 9;15(1):404. doi: 10.1038/s41467-023-44211-0. Nat Commun. 2024. PMID: 38195739 Free PMC article.
The plasmablast response to SARS-CoV-2 mRNA vaccination is dominated by non-neutralizing antibodies and targets both the NTD and the RBD.
Amanat F, Thapa M, Lei T, Sayed Ahmed SM, Adelsberg DC, Carreno JM, Strohmeier S, Schmitz AJ, Zafar S, Zhou JQ, Rijnink W, Alshammary H, Borcherding N, Reiche AG, Srivastava K, Sordillo EM, van Bakel H; Personalized Virology Initiative; Turner JS, Bajic G, Simon V, Ellebedy AH, Krammer F. Amanat F, et al. Among authors: van bakel h. medRxiv [Preprint]. 2021 May 1:2021.03.07.21253098. doi: 10.1101/2021.03.07.21253098. medRxiv. 2021. PMID: 33758878 Free PMC article. Preprint.
A robust, highly multiplexed mass spectrometry assay to identify SARS-CoV-2 variants.
Hernandez MM, Banu R, Shrestha P, Gonzalez-Reiche AS, van de Guchte A, Farrugia K, Sebra R; Mount Sinai PSP Study Group; Gitman MR, Nowak MD, Cordon-Cardo C, Simon V, van Bakel H, Sordillo EM, Luna N, Ramirez A, Castañeda SA, Patiño LH, Ballesteros N, Muñoz M, Ramírez JD, Paniz-Mondolfi AE. Hernandez MM, et al. Among authors: van bakel h, van de guchte a. medRxiv [Preprint]. 2022 May 29:2022.05.28.22275691. doi: 10.1101/2022.05.28.22275691. medRxiv. 2022. PMID: 35665019 Free PMC article. Updated. Preprint.
The impact of S2 mutations on Omicron SARS-CoV-2 cell surface expression and fusogenicity.
Escalera A, Laporte M, Turner S, Karakus U, Gonzalez-Reiche AS, van de Guchte A, Farrugia K, Khalil Z, van Bakel H, Smith D, García-Sastre A, Aydillo T. Escalera A, et al. Among authors: van bakel h, van de guchte a. Emerg Microbes Infect. 2024 Dec;13(1):2297553. doi: 10.1080/22221751.2023.2297553. Epub 2024 Feb 13. Emerg Microbes Infect. 2024. PMID: 38112266 Free PMC article.
SARS-CoV-2-infection- and vaccine-induced antibody responses are long lasting with an initial waning phase followed by a stabilization phase.
Srivastava K, Carreño JM, Gleason C, Monahan B, Singh G, Abbad A, Tcheou J, Raskin A, Kleiner G, van Bakel H, Sordillo EM; PARIS Study Group; Krammer F, Simon V. Srivastava K, et al. Among authors: van bakel h. Immunity. 2024 Mar 12;57(3):587-599.e4. doi: 10.1016/j.immuni.2024.01.017. Epub 2024 Feb 22. Immunity. 2024. PMID: 38395697 Free PMC article.
Host-microbe multiomic profiling reveals age-dependent immune dysregulation associated with COVID-19 immunopathology.
Phan HV, Tsitsiklis A, Maguire CP, Haddad EK, Becker PM, Kim-Schulze S, Lee B, Chen J, Hoch A, Pickering H, van Zalm P, Altman MC, Augustine AD, Calfee CS, Bosinger S, Cairns CB, Eckalbar W, Guan L, Jayavelu ND, Kleinstein SH, Krammer F, Maecker HT, Ozonoff A, Peters B, Rouphael N; IMPACC Network; Montgomery RR, Reed E, Schaenman J, Steen H, Levy O, Diray-Arce J, Langelier CR. Phan HV, et al. Sci Transl Med. 2024 Apr 17;16(743):eadj5154. doi: 10.1126/scitranslmed.adj5154. Epub 2024 Apr 17. Sci Transl Med. 2024. PMID: 38630846
Integrated longitudinal multiomics study identifies immune programs associated with acute COVID-19 severity and mortality.
Gygi JP, Maguire C, Patel RK, Shinde P, Konstorum A, Shannon CP, Xu L, Hoch A, Jayavelu ND, Haddad EK; IMPACC Network; Reed EF, Kraft M, McComsey GA, Metcalf JP, Ozonoff A, Esserman D, Cairns CB, Rouphael N, Bosinger SE, Kim-Schulze S, Krammer F, Rosen LB, van Bakel H, Wilson M, Eckalbar WL, Maecker HT, Langelier CR, Steen H, Altman MC, Montgomery RR, Levy O, Melamed E, Pulendran B, Diray-Arce J, Smolen KK, Fragiadakis GK, Becker PM, Sekaly RP, Ehrlich LI, Fourati S, Peters B, Kleinstein SH, Guan L. Gygi JP, et al. Among authors: van bakel h. J Clin Invest. 2024 May 1;134(9):e176640. doi: 10.1172/JCI176640. J Clin Invest. 2024. PMID: 38690733 Free PMC article. Clinical Trial.
Mapping SARS-CoV-2 antigenic relationships and serological responses.
Wilks SH, Mühlemann B, Shen X, Türeli S, LeGresley EB, Netzl A, Caniza MA, Chacaltana-Huarcaya JN, Corman VM, Daniell X, Datto MB, Dawood FS, Denny TN, Drosten C, Fouchier RAM, Garcia PJ, Halfmann PJ, Jassem A, Jeworowski LM, Jones TC, Kawaoka Y, Krammer F, McDanal C, Pajon R, Simon V, Stockwell MS, Tang H, van Bakel H, Veguilla V, Webby R, Montefiori DC, Smith DJ. Wilks SH, et al. Among authors: van bakel h. bioRxiv [Preprint]. 2023 Jun 16:2022.01.28.477987. doi: 10.1101/2022.01.28.477987. bioRxiv. 2023. PMID: 35860221 Free PMC article. Updated. Preprint.
No Remdesivir Resistance Observed in the Phase 3 Severe and Moderate COVID-19 SIMPLE Trials.
Hedskog C, Spinner CD, Protzer U, Hoffmann D, Ko C, Gottlieb RL, Askar M, Roestenberg M, de Vries JJC, Carbo EC, Martin R, Li J, Han D, Rodriguez L, Parvangada A, Perry JK, Ferrer R, Antón A, Andrés C, Casares V, Günthard HF, Huber M, McComsey GA, Sadri N, Aberg JA, van Bakel H, Porter DP. Hedskog C, et al. Among authors: van bakel h. Viruses. 2024 Mar 31;16(4):546. doi: 10.3390/v16040546. Viruses. 2024. PMID: 38675889 Free PMC article. Clinical Trial.
An immune correlate of SARS-CoV-2 infection and severity of reinfections.
Maier HE, Balmaseda A, Ojeda S, Cerpas C, Sanchez N, Plazaola M, van Bakel H, Kubale J, Lopez R, Saborio S, Barilla C; PSP Study Group; Harris E, Kuan G, Gordon A. Maier HE, et al. Among authors: van bakel h. medRxiv [Preprint]. 2021 Nov 24:2021.11.23.21266767. doi: 10.1101/2021.11.23.21266767. medRxiv. 2021. PMID: 34845458 Free PMC article. Preprint.
239 results