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Cleavage of the Jaw1 C-terminal region enhances its augmentative effect on the Ca2+ release via IP3 receptors.
Kozono T, Jogano C, Okumura W, Sato H, Matsui H, Takagi T, Okumura N, Takao T, Tonozuka T, Nishikawa A. Kozono T, et al. J Cell Sci. 2023 Feb 15;136(4):jcs260439. doi: 10.1242/jcs.260439. Epub 2023 Feb 15. J Cell Sci. 2023. PMID: 36789796
Jaw1 (also known as IRAG2), a tail-anchored protein with 39 carboxyl (C)-terminal amino acids, is oriented to the lumen of the endoplasmic reticulum and outer nuclear membrane. We previously reported that Jaw1, as a member of the KASH protein family, plays a role in …
Jaw1 (also known as IRAG2), a tail-anchored protein with 39 carboxyl (C)-terminal amino acids, is oriented to the lumen of the endoplasmic r …
MiT/TFE family members suppress L-leucyl-L-leucine methyl ester-induced cell death.
Yabuki A, Miyara M, Umeda-Miyara K, Takao S, Sanoh S, Kotake Y. Yabuki A, et al. J Toxicol Sci. 2021;46(3):143-156. doi: 10.2131/jts.46.143. J Toxicol Sci. 2021. PMID: 33642520 Free article.
In this study, we confirmed that LLOMe-induced lysosomal damage triggered nuclear translocation of TFEB/TFE3/MITF and increased the mRNA levels of their target genes encoding lysosomal hydrolases and lysosomal membrane proteins in HeLa cells. ...Our results suggest that Mi …
In this study, we confirmed that LLOMe-induced lysosomal damage triggered nuclear translocation of TFEB/TFE3/MITF and increased the m …
LDB1 and the SWI/SNF complex participate in both transcriptional activation and repression by Caenorhabditis elegans BLIMP1/PRDM1.
Fong HT, Hagen T, Inoue T. Fong HT, et al. Biochim Biophys Acta Gene Regul Mech. 2020 Sep;1863(9):194577. doi: 10.1016/j.bbagrm.2020.194577. Epub 2020 May 14. Biochim Biophys Acta Gene Regul Mech. 2020. PMID: 32417234
Transcription factors of the BLIMP1/PRDM1 family are important regulators of development. BLIMP1/PRDM1 can both activate and repress gene expression, however, the mechanism of activation is not well understood. ...LDB-1 is the sole C. elegans member of the LIM Binding Prot …
Transcription factors of the BLIMP1/PRDM1 family are important regulators of development. BLIMP1/PRDM1 can both activate and repress …
Molecular and Crystal Structures of Uranyl Nitrate Coordination Polymers with Double-Headed 2-Pyrrolidone Derivatives.
Kazama H, Tsushima S, Ikeda Y, Takao K. Kazama H, et al. Inorg Chem. 2017 Nov 6;56(21):13530-13534. doi: 10.1021/acs.inorgchem.7b02250. Inorg Chem. 2017. PMID: 29064684
The solubility of [UO(2)(NO(3))(2)(DHNRP)](n) is no longer correlated to the hydrophobicity of the ligand but is exclusively governed by the ligand symmetry and packing efficiency. The newly designed DHNRP family can be used to establish a new spent nuclear fuel rep …
The solubility of [UO(2)(NO(3))(2)(DHNRP)](n) is no longer correlated to the hydrophobicity of the ligand but is exclusively governed by the …
Phospholipid methylation controls Atg32-mediated mitophagy and Atg8 recycling.
Sakakibara K, Eiyama A, Suzuki SW, Sakoh-Nakatogawa M, Okumura N, Tani M, Hashimoto A, Nagumo S, Kondo-Okamoto N, Kondo-Kakuta C, Asai E, Kirisako H, Nakatogawa H, Kuge O, Takao T, Ohsumi Y, Okamoto K. Sakakibara K, et al. EMBO J. 2015 Nov 3;34(21):2703-19. doi: 10.15252/embj.201591440. Epub 2015 Oct 5. EMBO J. 2015. PMID: 26438722 Free PMC article.
Identification of cargo proteins specific for importin-β with importin-α applying a stable isotope labeling by amino acids in cell culture (SILAC)-based in vitro transport system.
Kimura M, Okumura N, Kose S, Takao T, Imamoto N. Kimura M, et al. J Biol Chem. 2013 Aug 23;288(34):24540-9. doi: 10.1074/jbc.M113.489286. Epub 2013 Jul 11. J Biol Chem. 2013. PMID: 23846694 Free PMC article.
The human importin (Imp)-beta family consists of 21 nucleocytoplasmic transport carrier proteins, which transport thousands of proteins (cargoes) across the nuclear envelope through nuclear pores in specific directions. To understand the nucleocytoplasmic tra …
The human importin (Imp)-beta family consists of 21 nucleocytoplasmic transport carrier proteins, which transport thousands of protei …
Identification of cargo proteins specific for the nucleocytoplasmic transport carrier transportin by combination of an in vitro transport system and stable isotope labeling by amino acids in cell culture (SILAC)-based quantitative proteomics.
Kimura M, Kose S, Okumura N, Imai K, Furuta M, Sakiyama N, Tomii K, Horton P, Takao T, Imamoto N. Kimura M, et al. Mol Cell Proteomics. 2013 Jan;12(1):145-57. doi: 10.1074/mcp.M112.019414. Epub 2012 Oct 19. Mol Cell Proteomics. 2013. PMID: 23087160 Free PMC article.
The human importin-beta family consists of 21 nucleocytoplasmic transport carrier proteins that carry proteins and RNAs across the nuclear envelope through nuclear pores in specific directions. ...In this step, the reaction system is first depleted of all imp …
The human importin-beta family consists of 21 nucleocytoplasmic transport carrier proteins that carry proteins and RNAs across the …
Inhibitors of the Ca(2+)/calmodulin-dependent protein kinase phosphatase family (CaMKP and CaMKP-N).
Sueyoshi N, Takao T, Nimura T, Sugiyama Y, Numano T, Shigeri Y, Taniguchi T, Kameshita I, Ishida A. Sueyoshi N, et al. Biochem Biophys Res Commun. 2007 Nov 23;363(3):715-21. doi: 10.1016/j.bbrc.2007.09.022. Epub 2007 Sep 18. Biochem Biophys Res Commun. 2007. PMID: 17897624
Ca(2+)/calmodulin-dependent protein kinase phosphatase (CaMKP) and its nuclear isoform CaMKP-N are unique Ser/Thr protein phosphatases that negatively regulate the Ca(2+)/calmodulin-dependent protein kinase (CaMK) cascade by dephosphorylating multifunctional CaMKI, II, and …
Ca(2+)/calmodulin-dependent protein kinase phosphatase (CaMKP) and its nuclear isoform CaMKP-N are unique Ser/Thr protein phosphatase …
Expression of NF-kappaB in epidermis and the relationship between NF-kappaB activation and inhibition of keratinocyte growth.
Takao J, Yudate T, Das A, Shikano S, Bonkobara M, Ariizumi K, Cruz PD. Takao J, et al. Br J Dermatol. 2003 Apr;148(4):680-8. doi: 10.1046/j.1365-2133.2003.05285.x. Br J Dermatol. 2003. PMID: 12752124
BACKGROUND: Nuclear factor-kappaB (NF-kappaB) is a transcription factor involved in a number of signalling pathways in many cell types. ...NF-kB activation was examined in keratinocytes treated with various modulating agents by electrophoretic mobility shift assay (for DNA …
BACKGROUND: Nuclear factor-kappaB (NF-kappaB) is a transcription factor involved in a number of signalling pathways in many cell type …
13 results