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1975 3
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1984 28
1985 25
1986 50
1987 39
1988 43
1989 37
1990 47
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1997 50
1998 49
1999 43
2000 38
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2002 38
2003 46
2004 45
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2007 58
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2009 99
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2016 95
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2,234 results

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Page 1
Cell transformation by the middle T-antigen of polyoma virus.
Ichaso N, Dilworth SM. Ichaso N, et al. Oncogene. 2001 Nov 26;20(54):7908-16. doi: 10.1038/sj.onc.1204859. Oncogene. 2001. PMID: 11753673 Review.
The polyoma virus region expressed early in the lytic cycle encodes three proteins, or T-antigens, that together cause the infected cell to enter the cell cycle and so provide a suitable cellular environment for replication of the viral genome. ...Most of this trans …
The polyoma virus region expressed early in the lytic cycle encodes three proteins, or T-antigens, that together cause the inf …
Lessons from polyoma middle T antigen on signaling and transformation: A DNA tumor virus contribution to the war on cancer.
Schaffhausen BS, Roberts TM. Schaffhausen BS, et al. Virology. 2009 Feb 20;384(2):304-16. doi: 10.1016/j.virol.2008.09.042. Epub 2008 Nov 20. Virology. 2009. PMID: 19022468 Free PMC article. Review.
Middle T antigen (MT) is the principal oncogene of murine polyomavirus. ...
Middle T antigen (MT) is the principal oncogene of murine polyomavirus. ...
Polyoma viral middle T-antigen is required for transformation.
Mes AM, Hassell JA. Mes AM, et al. J Virol. 1982 May;42(2):621-9. doi: 10.1128/JVI.42.2.621-629.1982. J Virol. 1982. PMID: 6283174 Free PMC article.
To determine whether small or middle T-antigen (or both) of polyoma virus is required for transformation, we constructed mutants of recombinant plasmids which bear the viral oncogene and measured the capacity of these mutants to transform rat cells in culture …
To determine whether small or middle T-antigen (or both) of polyoma virus is required for transformation, we constructe …
The complex of polyoma virus middle-T antigen and pp60c-src.
Courtneidge SA, Smith AE. Courtneidge SA, et al. EMBO J. 1984 Mar;3(3):585-91. doi: 10.1002/j.1460-2075.1984.tb01852.x. EMBO J. 1984. PMID: 6325177 Free PMC article.
We have recently proposed that the transforming protein of polyoma virus, middle-T antigen, forms a complex with pp60c-src. Here we provide additional evidence for the existence of the complex using both monoclonal antibodies specific for middle-T …
We have recently proposed that the transforming protein of polyoma virus, middle-T antigen, forms a complex with pp60c- …
Association of phosphatidylinositol kinase activity with polyoma middle-T competent for transformation.
Whitman M, Kaplan DR, Schaffhausen B, Cantley L, Roberts TM. Whitman M, et al. Nature. 1985 May 16-22;315(6016):239-42. doi: 10.1038/315239a0. Nature. 1985. PMID: 2987699
Polyoma middle-T antigen is required for viral transformation of cultured cells and for tumorigenesis in animals. ...Here, we assayed for PI kinase activity in immunoprecipitates made with middle-T- or pp60c-src-specific antisera of cells infect …
Polyoma middle-T antigen is required for viral transformation of cultured cells and for tumorigenesis in animals. ...He …
Transmission of the polyoma virus middle T gene as the oncogene of a murine retrovirus.
Donoghue DJ, Anderson C, Hunter T, Kaplan PL. Donoghue DJ, et al. Nature. 1984 Apr 19-25;308(5961):748-50. doi: 10.1038/308748a0. Nature. 1984. PMID: 6325917
The ability of polyoma virus to transform infected cells is determined by genes that encode the large, middle and small T antigens and which are found in the early region of the virus genome. ...During the life cycle of this recombinant virus the intervening …
The ability of polyoma virus to transform infected cells is determined by genes that encode the large, middle and small T …
Polyoma small and middle T antigens and SV40 small t antigen form stable complexes with protein phosphatase 2A.
Pallas DC, Shahrik LK, Martin BL, Jaspers S, Miller TB, Brautigan DL, Roberts TM. Pallas DC, et al. Cell. 1990 Jan 12;60(1):167-76. doi: 10.1016/0092-8674(90)90726-u. Cell. 1990. PMID: 2153055
We have purified the 36 and 63 kd cellular proteins known to associate with polyomavirus middle and small tumor (T) antigens and SV40 small t antigen. ...Finally, the 36 kd PP2A catalytic subunit can be immunoprecipitated by anti-pp60c-src antisera onl …
We have purified the 36 and 63 kd cellular proteins known to associate with polyomavirus middle and small tumor (T) ant …
Comparison of phosphorylation of two polyoma virus middle T antigens in vivo and in vitro.
Schaffhausen B, Benjamin TL. Schaffhausen B, et al. J Virol. 1981 Oct;40(1):184-96. doi: 10.1128/JVI.40.1.184-196.1981. J Virol. 1981. PMID: 6169848 Free PMC article.
Two species of polyoma virus middle T antigen were detected in both lytically infected and transformed cells by in vitro kinase assay of immunoprecipitates. ...Phenotypically normal revertant cells of a polyoma transformed line failed to express any …
Two species of polyoma virus middle T antigen were detected in both lytically infected and transformed cells by in vitr …
Middle T antigen as primary inducer of full expression of the phenotype of transformation by polyoma virus.
Ito Y, Spurr N, Griffin BE. Ito Y, et al. J Virol. 1980 Jul;35(1):219-32. doi: 10.1128/JVI.35.1.219-232.1980. J Virol. 1980. PMID: 6251270 Free PMC article.
A large number of polyoma virus-transformed cells of rat, mouse, and hamster origin were examined for presence of T-antigen species. ...The deletions in the DNA of these mutants resulted in the shortening of the large and middle T antigens simultaneous …
A large number of polyoma virus-transformed cells of rat, mouse, and hamster origin were examined for presence of T-antigen sp …
2,234 results