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Senescence-Induced Vascular Remodeling Creates Therapeutic Vulnerabilities in Pancreas Cancer.
Ruscetti M, Morris JP 4th, Mezzadra R, Russell J, Leibold J, Romesser PB, Simon J, Kulick A, Ho YJ, Fennell M, Li J, Norgard RJ, Wilkinson JE, Alonso-Curbelo D, Sridharan R, Heller DA, de Stanchina E, Stanger BZ, Sherr CJ, Lowe SW. Ruscetti M, et al. Among authors: de stanchina e. Cell. 2020 Apr 16;181(2):424-441.e21. doi: 10.1016/j.cell.2020.03.008. Epub 2020 Mar 31. Cell. 2020. PMID: 32234521 Free PMC article.
E1A signaling to p53 involves the p19(ARF) tumor suppressor.
de Stanchina E, McCurrach ME, Zindy F, Shieh SY, Ferbeyre G, Samuelson AV, Prives C, Roussel MF, Sherr CJ, Lowe SW. de Stanchina E, et al. Genes Dev. 1998 Aug 1;12(15):2434-42. doi: 10.1101/gad.12.15.2434. Genes Dev. 1998. PMID: 9694807 Free PMC article.
Oncogenic ras and p53 cooperate to induce cellular senescence.
Ferbeyre G, de Stanchina E, Lin AW, Querido E, McCurrach ME, Hannon GJ, Lowe SW. Ferbeyre G, et al. Among authors: de stanchina e. Mol Cell Biol. 2002 May;22(10):3497-508. doi: 10.1128/MCB.22.10.3497-3508.2002. Mol Cell Biol. 2002. PMID: 11971980 Free PMC article.
Chk2 is a tumor suppressor that regulates apoptosis in both an ataxia telangiectasia mutated (ATM)-dependent and an ATM-independent manner.
Hirao A, Cheung A, Duncan G, Girard PM, Elia AJ, Wakeham A, Okada H, Sarkissian T, Wong JA, Sakai T, De Stanchina E, Bristow RG, Suda T, Lowe SW, Jeggo PA, Elledge SJ, Mak TW. Hirao A, et al. Among authors: de stanchina e. Mol Cell Biol. 2002 Sep;22(18):6521-32. doi: 10.1128/MCB.22.18.6521-6532.2002. Mol Cell Biol. 2002. PMID: 12192050 Free PMC article.
Tumour suppression: something for nothing?
de Stanchina E, Lowe SW. de Stanchina E, et al. Nat Cell Biol. 2002 Dec;4(12):E275-6. doi: 10.1038/ncb1202-e275. Nat Cell Biol. 2002. PMID: 12461528 No abstract available.
Survival signalling by Akt and eIF4E in oncogenesis and cancer therapy.
Wendel HG, De Stanchina E, Fridman JS, Malina A, Ray S, Kogan S, Cordon-Cardo C, Pelletier J, Lowe SW. Wendel HG, et al. Among authors: de stanchina e. Nature. 2004 Mar 18;428(6980):332-7. doi: 10.1038/nature02369. Nature. 2004. PMID: 15029198 Free article.
243 results