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Antiviral activity of natural phenolic compounds in complex at an allosteric site of SARS-CoV-2 papain-like protease.
Srinivasan V, Brognaro H, Prabhu PR, de Souza EE, Günther S, Reinke PYA, Lane TJ, Ginn H, Han H, Ewert W, Sprenger J, Koua FHM, Falke S, Werner N, Andaleeb H, Ullah N, Franca BA, Wang M, Barra ALC, Perbandt M, Schwinzer M, Schmidt C, Brings L, Lorenzen K, Schubert R, Machado RRG, Candido ED, Oliveira DBL, Durigon EL, Niebling S, Garcia AS, Yefanov O, Lieske J, Gelisio L, Domaracky M, Middendorf P, Groessler M, Trost F, Galchenkova M, Mashhour AR, Saouane S, Hakanpää J, Wolf M, Alai MG, Turk D, Pearson AR, Chapman HN, Hinrichs W, Wrenger C, Meents A, Betzel C. Srinivasan V, et al. Among authors: de souza ee. Commun Biol. 2022 Aug 11;5(1):805. doi: 10.1038/s42003-022-03737-7. Commun Biol. 2022. PMID: 35953531 Free PMC article.
Targeting SUMOylation in Plasmodium as a Potential Target for Malaria Therapy.
Sumam de Oliveira D, Kronenberger T, Palmisano G, Wrenger C, de Souza EE. Sumam de Oliveira D, et al. Among authors: de souza ee. Front Cell Infect Microbiol. 2021 Jun 10;11:685866. doi: 10.3389/fcimb.2021.685866. eCollection 2021. Front Cell Infect Microbiol. 2021. PMID: 34178724 Free PMC article. Review.
Hemorrhagic fever viruses: Pathogenesis, therapeutics, and emerging and re-emerging potential.
Flórez-Álvarez L, de Souza EE, Botosso VF, de Oliveira DBL, Ho PL, Taborda CP, Palmisano G, Capurro ML, Pinho JRR, Ferreira HL, Minoprio P, Arruda E, de Souza Ferreira LC, Wrenger C, Durigon EL. Flórez-Álvarez L, et al. Among authors: de souza ee. Front Microbiol. 2022 Oct 25;13:1040093. doi: 10.3389/fmicb.2022.1040093. eCollection 2022. Front Microbiol. 2022. PMID: 36386719 Free PMC article. Review.
Protein Arginylation Is Regulated during SARS-CoV-2 Infection.
Macedo-da-Silva J, Rosa-Fernandes L, Gomes VM, Santiago VF, Santos DM, Molnar CMS, Barboza BR, de Souza EE, Marques RF, Boscardin SB, Durigon EL, Marinho CRF, Wrenger C, Marie SKN, Palmisano G. Macedo-da-Silva J, et al. Among authors: de souza ee. Viruses. 2023 Jan 19;15(2):290. doi: 10.3390/v15020290. Viruses. 2023. PMID: 36851505 Free PMC article.
Virulence Profiles of Wild-Type, P.1 and Delta SARS-CoV-2 Variants in K18-hACE2 Transgenic Mice.
da Silva Santos Y, Gamon THM, de Azevedo MSP, Telezynski BL, de Souza EE, de Oliveira DBL, Dombrowski JG, Rosa-Fernandes L, Palmisano G, de Moura Carvalho LJ, Luvizotto MCR, Wrenger C, Covas DT, Curi R, Marinho CRF, Durigon EL, Epiphanio S. da Silva Santos Y, et al. Among authors: de souza ee. Viruses. 2023 Apr 19;15(4):999. doi: 10.3390/v15040999. Viruses. 2023. PMID: 37112979 Free PMC article.
Calpeptin is a potent cathepsin inhibitor and drug candidate for SARS-CoV-2 infections.
Reinke PYA, de Souza EE, Günther S, Falke S, Lieske J, Ewert W, Loboda J, Herrmann A, Rahmani Mashhour A, Karničar K, Usenik A, Lindič N, Sekirnik A, Botosso VF, Santelli GMM, Kapronezai J, de Araújo MV, Silva-Pereira TT, Filho AFS, Tavares MS, Flórez-Álvarez L, de Oliveira DBL, Durigon EL, Giaretta PR, Heinemann MB, Hauser M, Seychell B, Böhler H, Rut W, Drag M, Beck T, Cox R, Chapman HN, Betzel C, Brehm W, Hinrichs W, Ebert G, Latham SL, Guimarães AMS, Turk D, Wrenger C, Meents A. Reinke PYA, et al. Among authors: de souza ee. Commun Biol. 2023 Oct 18;6(1):1058. doi: 10.1038/s42003-023-05317-9. Commun Biol. 2023. PMID: 37853179 Free PMC article.
Enhanced Immunogenicity and Protective Effects against SARS-CoV-2 Following Immunization with a Recombinant RBD-IgG Chimeric Protein.
Silva MO, Castro-Amarante MF, Venceslau-Carvalho AA, Almeida BDS, Daher IP, Souza-Silva GA, Yamamoto MM, Koike G, de Souza EE, Wrenger C, Ferreira LCS, Boscardin SB. Silva MO, et al. Among authors: de souza ee. Vaccines (Basel). 2024 Mar 27;12(4):356. doi: 10.3390/vaccines12040356. Vaccines (Basel). 2024. PMID: 38675739 Free PMC article.
High Target Homology Does Not Guarantee Inhibition: Aminothiazoles Emerge as Inhibitors of Plasmodium falciparum.
Johannsen S, Gierse RM, Krüger A, Edwards RL, Nanna V, Fontana A, Zhu D, Masini T, de Carvalho LP, Poizat M, Kieftenbelt B, Hodge DM, Alvarez S, Bunt D, Lacour A, Shams A, Meissner KA, de Souza EE, Dröge M, van Vliet B, den Hartog J, Hutter MC, Held J, Odom John AR, Wrenger C, Hirsch AKH. Johannsen S, et al. Among authors: de souza ee. ACS Infect Dis. 2024 Mar 8;10(3):1000-1022. doi: 10.1021/acsinfecdis.3c00670. Epub 2024 Feb 17. ACS Infect Dis. 2024. PMID: 38367280 Free PMC article.
20 results