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Frequency and Genomic Aspects of Intrinsic Resistance to Vismodegib in Locally Advanced Basal Cell Carcinoma.
Yurchenko AA, Pop OT, Ighilahriz M, Padioleau I, Rajabi F, Sharpe HJ, Poulalhon N, Dreno B, Khammari A, Delord M, Alberti A, Soufir N, Battistella M, Mourah S, Bouquet F, Savina A, Besse A, Mendez-Lopez M, Grange F, Monestier S, Mortier L, Meyer N, Dutriaux C, Robert C, Saiag P, Herms F, Lambert J, de Sauvage FJ, Dumaz N, Flatz L, Basset-Seguin N, Nikolaev SI. Yurchenko AA, et al. Among authors: de sauvage fj. Clin Cancer Res. 2022 Apr 1;28(7):1422-1432. doi: 10.1158/1078-0432.CCR-21-3764. Clin Cancer Res. 2022. PMID: 35078858 Free PMC article.
Activating Smoothened mutations in sporadic basal-cell carcinoma.
Xie J, Murone M, Luoh SM, Ryan A, Gu Q, Zhang C, Bonifas JM, Lam CW, Hynes M, Goddard A, Rosenthal A, Epstein EH Jr, de Sauvage FJ. Xie J, et al. Among authors: de sauvage fj. Nature. 1998 Jan 1;391(6662):90-2. doi: 10.1038/34201. Nature. 1998. PMID: 9422511
The hedgehog signaling pathway in cancer.
Evangelista M, Tian H, de Sauvage FJ. Evangelista M, et al. Among authors: de sauvage fj. Clin Cancer Res. 2006 Oct 15;12(20 Pt 1):5924-8. doi: 10.1158/1078-0432.CCR-06-1736. Clin Cancer Res. 2006. PMID: 17062662 Review.
Paracrine Hedgehog signaling in cancer.
Theunissen JW, de Sauvage FJ. Theunissen JW, et al. Among authors: de sauvage fj. Cancer Res. 2009 Aug 1;69(15):6007-10. doi: 10.1158/0008-5472.CAN-09-0756. Epub 2009 Jul 28. Cancer Res. 2009. PMID: 19638582 Review.
Smoothened mutation confers resistance to a Hedgehog pathway inhibitor in medulloblastoma.
Yauch RL, Dijkgraaf GJ, Alicke B, Januario T, Ahn CP, Holcomb T, Pujara K, Stinson J, Callahan CA, Tang T, Bazan JF, Kan Z, Seshagiri S, Hann CL, Gould SE, Low JA, Rudin CM, de Sauvage FJ. Yauch RL, et al. Among authors: de sauvage fj. Science. 2009 Oct 23;326(5952):572-4. doi: 10.1126/science.1179386. Epub 2009 Sep 2. Science. 2009. PMID: 19726788 Free PMC article.
Clinical experience with Hedgehog pathway inhibitors.
Low JA, de Sauvage FJ. Low JA, et al. Among authors: de sauvage fj. J Clin Oncol. 2010 Dec 20;28(36):5321-6. doi: 10.1200/JCO.2010.27.9943. Epub 2010 Nov 1. J Clin Oncol. 2010. PMID: 21041712
Targeting superficial or nodular Basal cell carcinoma with topically formulated small molecule inhibitor of smoothened.
Tang T, Tang JY, Li D, Reich M, Callahan CA, Fu L, Yauch RL, Wang F, Kotkow K, Chang KS, Shpall E, Wu A, Rubin LL, Marsters JC Jr, Epstein EH Jr, Caro I, de Sauvage FJ. Tang T, et al. Among authors: de sauvage fj. Clin Cancer Res. 2011 May 15;17(10):3378-87. doi: 10.1158/1078-0432.CCR-10-3370. Epub 2011 May 10. Clin Cancer Res. 2011. PMID: 21558397 Free PMC article. Clinical Trial.
184 results