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Neuroinvasion and anosmia are independent phenomena upon infection with SARS-CoV-2 and its variants.
de Melo GD, Perraud V, Alvarez F, Vieites-Prado A, Kim S, Kergoat L, Coleon A, Trüeb BS, Tichit M, Piazza A, Thierry A, Hardy D, Wolff N, Munier S, Koszul R, Simon-Lorière E, Thiel V, Lecuit M, Lledo PM, Renier N, Larrous F, Bourhy H. de Melo GD, et al. Nat Commun. 2023 Jul 26;14(1):4485. doi: 10.1038/s41467-023-40228-7. Nat Commun. 2023. PMID: 37495586 Free PMC article.
A combination of two human monoclonal antibodies cures symptomatic rabies.
de Melo GD, Sonthonnax F, Lepousez G, Jouvion G, Minola A, Zatta F, Larrous F, Kergoat L, Mazo C, Moigneu C, Aiello R, Salomoni A, Brisebard E, De Benedictis P, Corti D, Bourhy H. de Melo GD, et al. Among authors: de benedictis p. EMBO Mol Med. 2020 Nov 6;12(11):e12628. doi: 10.15252/emmm.202012628. Epub 2020 Sep 18. EMBO Mol Med. 2020. PMID: 32945125 Free PMC article.
[New aspects of rabies control].
Bourhy H, de Melo GD, Tarantola A. Bourhy H, et al. Among authors: de melo gd. Bull Acad Natl Med. 2020 Dec;204(9):1000-1009. doi: 10.1016/j.banm.2020.09.036. Epub 2020 Sep 18. Bull Acad Natl Med. 2020. PMID: 32981935 Free PMC article. Review. French.
COVID-19-related anosmia is associated with viral persistence and inflammation in human olfactory epithelium and brain infection in hamsters.
de Melo GD, Lazarini F, Levallois S, Hautefort C, Michel V, Larrous F, Verillaud B, Aparicio C, Wagner S, Gheusi G, Kergoat L, Kornobis E, Donati F, Cokelaer T, Hervochon R, Madec Y, Roze E, Salmon D, Bourhy H, Lecuit M, Lledo PM. de Melo GD, et al. Sci Transl Med. 2021 Jun 2;13(596):eabf8396. doi: 10.1126/scitranslmed.abf8396. Epub 2021 May 3. Sci Transl Med. 2021. PMID: 33941622 Free PMC article.
SARS-CoV-2 infection induces the dedifferentiation of multiciliated cells and impairs mucociliary clearance.
Robinot R, Hubert M, de Melo GD, Lazarini F, Bruel T, Smith N, Levallois S, Larrous F, Fernandes J, Gellenoncourt S, Rigaud S, Gorgette O, Thouvenot C, Trébeau C, Mallet A, Duménil G, Gobaa S, Etournay R, Lledo PM, Lecuit M, Bourhy H, Duffy D, Michel V, Schwartz O, Chakrabarti LA. Robinot R, et al. Among authors: de melo gd. Nat Commun. 2021 Jul 16;12(1):4354. doi: 10.1038/s41467-021-24521-x. Nat Commun. 2021. PMID: 34272374 Free PMC article.
A live measles-vectored COVID-19 vaccine induces strong immunity and protection from SARS-CoV-2 challenge in mice and hamsters.
Frantz PN, Barinov A, Ruffié C, Combredet C, Najburg V, de Melo GD, Larrous F, Kergoat L, Teeravechyan S, Jongkaewwattana A, Billon-Denis E, Tournier JN, Prot M, Levillayer L, Conquet L, Montagutelli X, Tichit M, Hardy D, Fernandes P, Strick-Marchand H, Di Santo J, Simon-Lorière E, Bourhy H, Tangy F. Frantz PN, et al. Among authors: de melo gd. Nat Commun. 2021 Nov 1;12(1):6277. doi: 10.1038/s41467-021-26506-2. Nat Commun. 2021. PMID: 34725327 Free PMC article.
Potent human broadly SARS-CoV-2-neutralizing IgA and IgG antibodies effective against Omicron BA.1 and BA.2.
Planchais C, Fernández I, Bruel T, de Melo GD, Prot M, Beretta M, Guardado-Calvo P, Dufloo J, Molinos-Albert LM, Backovic M, Chiaravalli J, Giraud E, Vesin B, Conquet L, Grzelak L, Planas D, Staropoli I, Guivel-Benhassine F, Hieu T, Boullé M, Cervantes-Gonzalez M, Ungeheuer MN, Charneau P, van der Werf S, Agou F; French COVID Cohort Study Group; CORSER Study Group; Dimitrov JD, Simon-Lorière E, Bourhy H, Montagutelli X, Rey FA, Schwartz O, Mouquet H. Planchais C, et al. Among authors: de melo gd. J Exp Med. 2022 Jul 4;219(7):e20220638. doi: 10.1084/jem.20220638. Epub 2022 Jun 15. J Exp Med. 2022. PMID: 35704748 Free PMC article.
34 results