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Biological activity of 2α,3β,23-trihydroxyolean-12-ene on glucose homeostasis.
Gomes Castro AJ, Cazarolli LH, Silva Frederico MJ, Dambrós BF, de Carvalho FK, de Medeiros Pinto VA, da Fonte Ramos C, Filippin Monteiro FB, Pizzolatti MG, Mena Barreto Silva FR. Gomes Castro AJ, et al. Among authors: de medeiros pinto va. Eur J Pharmacol. 2021 Sep 15;907:174250. doi: 10.1016/j.ejphar.2021.174250. Epub 2021 Jun 10. Eur J Pharmacol. 2021. PMID: 34118223 Free article.
The mechanism of action of ursolic acid as insulin secretagogue and insulinomimetic is mediated by cross-talk between calcium and kinases to regulate glucose balance.
Castro AJ, Frederico MJ, Cazarolli LH, Mendes CP, Bretanha LC, Schmidt ÉC, Bouzon ZL, de Medeiros Pinto VA, da Fonte Ramos C, Pizzolatti MG, Silva FR. Castro AJ, et al. Among authors: de medeiros pinto va. Biochim Biophys Acta. 2015 Jan;1850(1):51-61. doi: 10.1016/j.bbagen.2014.10.001. Epub 2014 Oct 13. Biochim Biophys Acta. 2015. PMID: 25312987 Free article.