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Telacebec (Q203), a New Antituberculosis Agent.
de Jager VR, Dawson R, van Niekerk C, Hutchings J, Kim J, Vanker N, van der Merwe L, Choi J, Nam K, Diacon AH. de Jager VR, et al. N Engl J Med. 2020 Mar 26;382(13):1280-1281. doi: 10.1056/NEJMc1913327. N Engl J Med. 2020. PMID: 32212527 Clinical Trial. No abstract available.
Optimizing β-Lactams against Tuberculosis.
de Jager VR, Vanker N, van der Merwe L, van Brakel E, Muliaditan M, Diacon AH. de Jager VR, et al. Am J Respir Crit Care Med. 2020 May 1;201(9):1155-1157. doi: 10.1164/rccm.201911-2149LE. Am J Respir Crit Care Med. 2020. PMID: 31922901 Free PMC article. No abstract available.
Fourteen-Day Bactericidal Activity, Safety, and Pharmacokinetics of Linezolid in Adults with Drug-Sensitive Pulmonary Tuberculosis.
Diacon AH, De Jager VR, Dawson R, Narunsky K, Vanker N, Burger DA, Everitt D, Pappas F, Nedelman J, Mendel CM. Diacon AH, et al. Among authors: de jager vr. Antimicrob Agents Chemother. 2020 Mar 24;64(4):e02012-19. doi: 10.1128/AAC.02012-19. Print 2020 Mar 24. Antimicrob Agents Chemother. 2020. PMID: 31988102 Free PMC article. Clinical Trial.
Reply to Kim et al., "Optimal Dose or Optimal Exposure? Consideration for Linezolid in Tuberculosis Treatment".
Diacon AH, De Jager VR, Dawson R, Narunsky K, Vanker N, Burger DA, Everitt D, Pappas F, Nedelman J, Mendel CM. Diacon AH, et al. Among authors: de jager vr. Antimicrob Agents Chemother. 2020 Jun 23;64(7):e00709-20. doi: 10.1128/AAC.00709-20. Print 2020 Jun 23. Antimicrob Agents Chemother. 2020. PMID: 32366714 Free PMC article. No abstract available.
Fourteen-day PET/CT imaging to monitor drug combination activity in treated individuals with tuberculosis.
Xie YL, de Jager VR, Chen RY, Dodd LE, Paripati P, Via LE, Follmann D, Wang J, Lumbard K, Lahouar S, Malherbe ST, Andrews J, Yu X, Goldfeder LC, Cai Y, Arora K, Loxton AG, Vanker N, Duvenhage M, Winter J, Song T, Walzl G, Diacon AH, Barry CE 3rd. Xie YL, et al. Among authors: de jager vr. Sci Transl Med. 2021 Feb 3;13(579):eabd7618. doi: 10.1126/scitranslmed.abd7618. Sci Transl Med. 2021. PMID: 33536283
Increased bactericidal activity but dose-limiting intolerability at 50 mg·kg-1 rifampicin.
Te Brake LHM, de Jager V, Narunsky K, Vanker N, Svensson EM, Phillips PPJ, Gillespie SH, Heinrich N, Hoelscher M, Dawson R, Diacon AH, Aarnoutse RE, Boeree MJ; PanACEA Consortium. Te Brake LHM, et al. Eur Respir J. 2021 Jul 8;58(1):2000955. doi: 10.1183/13993003.00955-2020. Print 2021 Jul. Eur Respir J. 2021. PMID: 33542056 Free PMC article.
20 results