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Delivery route, MyD88 signaling and cross-priming events determine the anti-tumor efficacy of an adenovirus based melanoma vaccine.
Hangalapura BN, Oosterhoff D, Gupta T, de Groot J, Wijnands PG, van Beusechem VW, den Haan J, Tüting T, van den Eertwegh AJ, Curiel DT, Scheper RJ, de Gruijl TD. Hangalapura BN, et al. Among authors: de groot j, de gruijl td. Vaccine. 2011 Mar 9;29(12):2313-21. doi: 10.1016/j.vaccine.2011.01.022. Epub 2011 Jan 25. Vaccine. 2011. PMID: 21272606 Free PMC article.
Glycan-modified liposomes boost CD4+ and CD8+ T-cell responses by targeting DC-SIGN on dendritic cells.
Unger WW, van Beelen AJ, Bruijns SC, Joshi M, Fehres CM, van Bloois L, Verstege MI, Ambrosini M, Kalay H, Nazmi K, Bolscher JG, Hooijberg E, de Gruijl TD, Storm G, van Kooyk Y. Unger WW, et al. Among authors: de gruijl td. J Control Release. 2012 May 30;160(1):88-95. doi: 10.1016/j.jconrel.2012.02.007. Epub 2012 Feb 15. J Control Release. 2012. PMID: 22366522
Notch controls generation and function of human effector CD8+ T cells.
Kuijk LM, Verstege MI, Rekers NV, Bruijns SC, Hooijberg E, Roep BO, de Gruijl TD, van Kooyk Y, Unger WW. Kuijk LM, et al. Among authors: de gruijl td. Blood. 2013 Apr 4;121(14):2638-46. doi: 10.1182/blood-2012-07-442962. Epub 2013 Feb 4. Blood. 2013. PMID: 23380742 Free article.
Intradermal delivery of TLR agonists in a human explant skin model: preferential activation of migratory dendritic cells by polyribosinic-polyribocytidylic acid and peptidoglycans.
Oosterhoff D, Heusinkveld M, Lougheed SM, Kosten I, Lindstedt M, Bruijns SC, van Es T, van Kooyk Y, van der Burg SH, de Gruijl TD. Oosterhoff D, et al. Among authors: de gruijl td. J Immunol. 2013 Apr 1;190(7):3338-45. doi: 10.4049/jimmunol.1200598. Epub 2013 Mar 6. J Immunol. 2013. PMID: 23467931 Free article.
IL-10 conditioning of human skin affects the distribution of migratory dendritic cell subsets and functional T cell differentiation.
Lindenberg JJ, Oosterhoff D, Sombroek CC, Lougheed SM, Hooijberg E, Stam AG, Santegoets SJ, Tijssen HJ, Buter J, Pinedo HM, van den Eertwegh AJ, Scheper RJ, Koenen HJ, van de Ven R, de Gruijl TD. Lindenberg JJ, et al. Among authors: de gruijl td. PLoS One. 2013 Jul 18;8(7):e70237. doi: 10.1371/journal.pone.0070237. Print 2013. PLoS One. 2013. PMID: 23875023 Free PMC article.
294 results