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Page 1
Yellow fever virus is susceptible to sofosbuvir both in vitro and in vivo.
de Freitas CS, Higa LM, Sacramento CQ, Ferreira AC, Reis PA, Delvecchio R, Monteiro FL, Barbosa-Lima G, James Westgarth H, Vieira YR, Mattos M, Rocha N, Hoelz LVB, Leme RPP, Bastos MM, Rodrigues GOL, Lopes CEM, Queiroz-Junior CM, Lima CX, Costa VV, Teixeira MM, Bozza FA, Bozza PT, Boechat N, Tanuri A, Souza TML. de Freitas CS, et al. PLoS Negl Trop Dis. 2019 Jan 30;13(1):e0007072. doi: 10.1371/journal.pntd.0007072. eCollection 2019 Jan. PLoS Negl Trop Dis. 2019. PMID: 30699122 Free PMC article.
Aureonitol, a Fungi-Derived Tetrahydrofuran, Inhibits Influenza Replication by Targeting Its Surface Glycoprotein Hemagglutinin.
Sacramento CQ, Marttorelli A, Fintelman-Rodrigues N, de Freitas CS, de Melo GR, Rocha ME, Kaiser CR, Rodrigues KF, da Costa GL, Alves CM, Santos-Filho O, Barbosa JP, Souza TM. Sacramento CQ, et al. Among authors: de freitas cs, de melo gr. PLoS One. 2015 Oct 13;10(10):e0139236. doi: 10.1371/journal.pone.0139236. eCollection 2015. PLoS One. 2015. PMID: 26462111 Free PMC article.
N-(2-(arylmethylimino)ethyl)-7-chloroquinolin-4-amine derivatives, synthesized by thermal and ultrasonic means, are endowed with anti-Zika virus activity.
Barbosa-Lima G, da Silveira Pinto LS, Kaiser CR, Wardell JL, De Freitas CS, Vieira YR, Marttorelli A, Cerbino Neto J, Bozza PT, Wardell SMSV, de Souza MVN, Souza TML. Barbosa-Lima G, et al. Among authors: de freitas cs, de souza mvn. Eur J Med Chem. 2017 Feb 15;127:434-441. doi: 10.1016/j.ejmech.2017.01.007. Epub 2017 Jan 6. Eur J Med Chem. 2017. PMID: 28092859
The clinically approved antiviral drug sofosbuvir inhibits Zika virus replication.
Sacramento CQ, de Melo GR, de Freitas CS, Rocha N, Hoelz LV, Miranda M, Fintelman-Rodrigues N, Marttorelli A, Ferreira AC, Barbosa-Lima G, Abrantes JL, Vieira YR, Bastos MM, de Mello Volotão E, Nunes EP, Tschoeke DA, Leomil L, Loiola EC, Trindade P, Rehen SK, Bozza FA, Bozza PT, Boechat N, Thompson FL, de Filippis AM, Brüning K, Souza TM. Sacramento CQ, et al. Among authors: de mello volotao e, de freitas cs, de filippis am, de melo gr. Sci Rep. 2017 Jan 18;7:40920. doi: 10.1038/srep40920. Sci Rep. 2017. PMID: 28098253 Free PMC article.
Corrigendum: The clinically approved antiviral drug sofosbuvir inhibits Zika virus replication.
Sacramento CQ, de Melo GR, de Freitas CS, Rocha N, Hoelz LVB, Miranda M, Fintelman-Rodrigues N, Marttorelli A, Ferreira AC, Barbosa-Lima G, Abrantes JL, Vieira YR, Bastos MM, Volotão EM, Nunes EP, Tschoeke DA, Leomil L, Loiola EC, Trindade P, Rehen SK, Bozza FA, Bozza PT, Boechat N, Thompson FL, de Filippis AMB, Brüning K, Souza TML. Sacramento CQ, et al. Among authors: de freitas cs, de filippis amb, de melo gr. Sci Rep. 2017 Apr 24;7:46772. doi: 10.1038/srep46772. Sci Rep. 2017. PMID: 28436989 Free PMC article. No abstract available.
Beyond Members of the Flaviviridae Family, Sofosbuvir Also Inhibits Chikungunya Virus Replication.
Ferreira AC, Reis PA, de Freitas CS, Sacramento CQ, Villas Bôas Hoelz L, Bastos MM, Mattos M, Rocha N, Gomes de Azevedo Quintanilha I, da Silva Gouveia Pedrosa C, Rocha Quintino Souza L, Correia Loiola E, Trindade P, Rangel Vieira Y, Barbosa-Lima G, de Castro Faria Neto HC, Boechat N, Rehen SK, Brüning K, Bozza FA, Bozza PT, Souza TML. Ferreira AC, et al. Among authors: de castro faria neto hc, de freitas cs. Antimicrob Agents Chemother. 2019 Jan 29;63(2):e01389-18. doi: 10.1128/AAC.01389-18. Print 2019 Feb. Antimicrob Agents Chemother. 2019. PMID: 30455237 Free PMC article.
Agathisflavone, a Biflavonoid from Anacardium occidentale L., Inhibits Influenza Virus Neuraminidase.
de Freitas CS, Rocha MEN, Sacramento CQ, Marttorelli A, Ferreira AC, Rocha N, de Oliveira AC, de Oliveira Gomes AM, Dos Santos PS, da Silva EO, da Costa JP, de Lima Moreira D, Bozza PT, Silva JL, Barroso SPC, Souza TML. de Freitas CS, et al. Among authors: de oliveira gomes am, de lima moreira d, de oliveira ac. Curr Top Med Chem. 2020;20(2):111-120. doi: 10.2174/1568026620666191219150738. Curr Top Med Chem. 2020. PMID: 31854280
Neuraminidase from Influenza A and B Viruses is Susceptible to the Compound 4-(4-Phenyl-1H-1,2,3-Triazol-1-yl)-2,2,6,6-Tetramethylpiperidine-1- Oxyl.
Sacramento CQ, Jordão AK, Abrantes JL, Alves CM, Marttorelli A, Fintelman-Rodrigues N, de Freitas CS, de Melo GR, Cunha AC, Ferreira VF, Souza TML. Sacramento CQ, et al. Among authors: de freitas cs, de melo gr. Curr Top Med Chem. 2020;20(2):132-139. doi: 10.2174/1568026620666191227142433. Curr Top Med Chem. 2020. PMID: 31880262
Atazanavir, Alone or in Combination with Ritonavir, Inhibits SARS-CoV-2 Replication and Proinflammatory Cytokine Production.
Fintelman-Rodrigues N, Sacramento CQ, Ribeiro Lima C, Souza da Silva F, Ferreira AC, Mattos M, de Freitas CS, Cardoso Soares V, da Silva Gomes Dias S, Temerozo JR, Miranda MD, Matos AR, Bozza FA, Carels N, Alves CR, Siqueira MM, Bozza PT, Souza TML. Fintelman-Rodrigues N, et al. Among authors: de freitas cs. Antimicrob Agents Chemother. 2020 Sep 21;64(10):e00825-20. doi: 10.1128/AAC.00825-20. Print 2020 Sep 21. Antimicrob Agents Chemother. 2020. PMID: 32759267 Free PMC article.
31 results