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Selenoneine-inspired selenohydantoins with glutathione peroxidase-like activity.
Alhasan R, Martins GM, de Castro PP, Saleem RSZ, Zaiter A, Fries-Raeth I, Kleinclauss A, Perrin-Sarrado C, Chaimbault P, da Silva Júnior EN, Gaucher C, Jacob C. Alhasan R, et al. Among authors: da silva junior en. Bioorg Med Chem. 2023 Oct 30;94:117479. doi: 10.1016/j.bmc.2023.117479. Epub 2023 Sep 20. Bioorg Med Chem. 2023. PMID: 37769443
Synthesis and anti-Trypanosoma cruzi activity of naphthoquinone-containing triazoles: electrochemical studies on the effects of the quinoidal moiety.
Diogo EB, Dias GG, Rodrigues BL, Guimarães TT, Valença WO, Camara CA, de Oliveira RN, da Silva MG, Ferreira VF, de Paiva YG, Goulart MO, Menna-Barreto RF, de Castro SL, da Silva Júnior EN. Diogo EB, et al. Among authors: da silva junior en, da silva mg. Bioorg Med Chem. 2013 Nov 1;21(21):6337-48. doi: 10.1016/j.bmc.2013.08.055. Epub 2013 Sep 6. Bioorg Med Chem. 2013. PMID: 24074878 Free article.
On the synthesis of quinone-based BODIPY hybrids: New insights on antitumor activity and mechanism of action in cancer cells.
Gontijo TB, de Freitas RP, Emery FS, Pedrosa LF, Vieira Neto JB, Cavalcanti BC, Pessoa C, King A, de Moliner F, Vendrell M, da Silva Júnior EN. Gontijo TB, et al. Among authors: da silva junior en. Bioorg Med Chem Lett. 2017 Sep 15;27(18):4446-4456. doi: 10.1016/j.bmcl.2017.08.007. Epub 2017 Aug 4. Bioorg Med Chem Lett. 2017. PMID: 28818447 Free article.
Natural product-inspired profluorophores for imaging NQO1 activity in tumour tissues.
Cheng Z, Valença WO, Dias GG, Scott J, Barth ND, de Moliner F, Souza GBP, Mellanby RJ, Vendrell M, da Silva Júnior EN. Cheng Z, et al. Among authors: da silva junior en. Bioorg Med Chem. 2019 Sep 1;27(17):3938-3946. doi: 10.1016/j.bmc.2019.07.017. Epub 2019 Jul 15. Bioorg Med Chem. 2019. PMID: 31327676
Design of hybrid molecules as antimycobacterial compounds: Synthesis of isoniazid-naphthoquinone derivatives and their activity against susceptible and resistant strains of Mycobacterium tuberculosis.
Reis WJ, Bozzi ÍAO, Ribeiro MF, Halicki PCB, Ferreira LA, Almeida da Silva PE, Ramos DF, de Simone CA, da Silva Júnior EN. Reis WJ, et al. Among authors: da silva junior en. Bioorg Med Chem. 2019 Sep 15;27(18):4143-4150. doi: 10.1016/j.bmc.2019.07.045. Epub 2019 Jul 27. Bioorg Med Chem. 2019. PMID: 31378595 Free article.
It takes two to tango: synthesis of cytotoxic quinones containing two redox active centers with potential antitumor activity.
Lima DJB, Almeida RG, Jardim GAM, Barbosa BPA, Santos ACC, Valença WO, Scheide MR, Gatto CC, de Carvalho GGC, Costa PMS, Pessoa C, Pereira CLM, Jacob C, Braga AL, da Silva Júnior EN. Lima DJB, et al. Among authors: da silva junior en. RSC Med Chem. 2021 Aug 12;12(10):1709-1721. doi: 10.1039/d1md00168j. eCollection 2021 Oct 20. RSC Med Chem. 2021. PMID: 34778772 Free PMC article.
84 results