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On the search for potential anti-Trypanosoma cruzi drugs: synthesis and biological evaluation of 2-hydroxy-3-methylamino and 1,2,3-triazolic naphthoquinoidal compounds obtained by click chemistry reactions.
da Silva Júnior EN, de Melo IM, Diogo EB, Costa VA, de Souza Filho JD, Valença WO, Camara CA, de Oliveira RN, de Araujo AS, Emery FS, dos Santos MR, de Simone CA, Menna-Barreto RF, de Castro SL. da Silva Júnior EN, et al. Eur J Med Chem. 2012 Jun;52:304-12. doi: 10.1016/j.ejmech.2012.03.039. Epub 2012 Mar 29. Eur J Med Chem. 2012. PMID: 22483633
Synthesis and anti-Trypanosoma cruzi activity of naphthoquinone-containing triazoles: electrochemical studies on the effects of the quinoidal moiety.
Diogo EB, Dias GG, Rodrigues BL, Guimarães TT, Valença WO, Camara CA, de Oliveira RN, da Silva MG, Ferreira VF, de Paiva YG, Goulart MO, Menna-Barreto RF, de Castro SL, da Silva Júnior EN. Diogo EB, et al. Among authors: da silva junior en, da silva mg. Bioorg Med Chem. 2013 Nov 1;21(21):6337-48. doi: 10.1016/j.bmc.2013.08.055. Epub 2013 Sep 6. Bioorg Med Chem. 2013. PMID: 24074878 Free article.
1,2,3-triazole-, arylamino- and thio-substituted 1,4-naphthoquinones: potent antitumor activity, electrochemical aspects, and bioisosteric replacement of C-ring-modified lapachones.
da Cruz EH, Hussene CM, Dias GG, Diogo EB, de Melo IM, Rodrigues BL, da Silva MG, Valença WO, Camara CA, de Oliveira RN, de Paiva YG, Goulart MO, Cavalcanti BC, Pessoa C, da Silva Júnior EN. da Cruz EH, et al. Among authors: da silva junior en, da silva mg. Bioorg Med Chem. 2014 Mar 1;22(5):1608-19. doi: 10.1016/j.bmc.2014.01.033. Epub 2014 Jan 31. Bioorg Med Chem. 2014. PMID: 24530030 Free article.
Antifungal activity of naphthoquinoidal compounds in vitro against fluconazole-resistant strains of different Candida species: a special emphasis on mechanisms of action on Candida tropicalis.
Neto JB, da Silva CR, Neta MA, Campos RS, Siebra JT, Silva RA, Gaspar DM, Magalhães HI, de Moraes MO, Lobo MD, Grangeiro TB, Carvalho TS, Diogo EB, da Silva Júnior EN, Rodrigues FA, Cavalcanti BC, Júnior HV. Neto JB, et al. Among authors: da silva cr, silva ra, da silva junior en, junior hv. PLoS One. 2014 May 9;9(5):e93698. doi: 10.1371/journal.pone.0093698. eCollection 2014. PLoS One. 2014. PMID: 24817320 Free PMC article.
Quinone-based fluorophores for imaging biological processes.
Dias GG, King A, de Moliner F, Vendrell M, da Silva Júnior EN. Dias GG, et al. Among authors: da silva junior en. Chem Soc Rev. 2018 Jan 2;47(1):12-27. doi: 10.1039/c7cs00553a. Chem Soc Rev. 2018. PMID: 29099127 Review.
Combination of Aryl Diselenides/Hydrogen Peroxide and Carbon-Nanotube/Rhodium Nanohybrids for Naphthol Oxidation: An Efficient Route towards Trypanocidal Quinones.
de Carvalho RL, Jardim GAM, Santos ACC, Araujo MH, Oliveira WXC, Bombaça ACS, Menna-Barreto RFS, Gopi E, Gravel E, Doris E, da Silva Júnior EN. de Carvalho RL, et al. Among authors: da silva junior en. Chemistry. 2018 Oct 12;24(57):15227-15235. doi: 10.1002/chem.201802773. Epub 2018 Sep 6. Chemistry. 2018. PMID: 29904959
84 results