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Mutations in ALK signaling pathways conferring resistance to ALK inhibitor treatment lead to collateral vulnerabilities in neuroblastoma cells.
Berlak M, Tucker E, Dorel M, Winkler A, McGearey A, Rodriguez-Fos E, da Costa BM, Barker K, Fyle E, Calton E, Eising S, Ober K, Hughes D, Koutroumanidou E, Carter P, Stankunaite R, Proszek P, Jain N, Rosswog C, Dorado-Garcia H, Molenaar JJ, Hubank M, Barone G, Anderson J, Lang P, Deubzer HE, Künkele A, Fischer M, Eggert A, Kloft C, Henssen AG, Boettcher M, Hertwig F, Blüthgen N, Chesler L, Schulte JH. Berlak M, et al. Among authors: da costa bm. Mol Cancer. 2022 Jun 10;21(1):126. doi: 10.1186/s12943-022-01583-z. Mol Cancer. 2022. PMID: 35689207 Free PMC article.
Therapeutic vulnerabilities in the DNA damage response for the treatment of ATRX mutant neuroblastoma.
George SL, Lorenzi F, King D, Hartlieb S, Campbell J, Pemberton H, Toprak UH, Barker K, Tall J, da Costa BM, van den Boogaard ML, Dolman MEM, Molenaar JJ, Bryant HE, Westermann F, Lord CJ, Chesler L. George SL, et al. Among authors: da costa bm. EBioMedicine. 2020 Sep;59:102971. doi: 10.1016/j.ebiom.2020.102971. Epub 2020 Aug 23. EBioMedicine. 2020. PMID: 32846370 Free PMC article.
In Vivo Modeling of Chemoresistant Neuroblastoma Provides New Insights into Chemorefractory Disease and Metastasis.
Yogev O, Almeida GS, Barker KT, George SL, Kwok C, Campbell J, Zarowiecki M, Kleftogiannis D, Smith LM, Hallsworth A, Berry P, Möcklinghoff T, Webber HT, Danielson LS, Buttery B, Calton EA, da Costa BM, Poon E, Jamin Y, Lise S, Veal GJ, Sebire N, Robinson SP, Anderson J, Chesler L. Yogev O, et al. Among authors: da costa bm. Cancer Res. 2019 Oct 15;79(20):5382-5393. doi: 10.1158/0008-5472.CAN-18-2759. Epub 2019 Aug 12. Cancer Res. 2019. PMID: 31405846
Indisulam targets RNA splicing and metabolism to serve as a therapeutic strategy for high-risk neuroblastoma.
Nijhuis A, Sikka A, Yogev O, Herendi L, Balcells C, Ma Y, Poon E, Eckold C, Valbuena GN, Xu Y, Liu Y, da Costa BM, Gruet M, Wickremesinghe C, Benito A, Kramer H, Montoya A, Carling D, Want EJ, Jamin Y, Chesler L, Keun HC. Nijhuis A, et al. Among authors: da costa bm. Nat Commun. 2022 Mar 16;13(1):1380. doi: 10.1038/s41467-022-28907-3. Nat Commun. 2022. PMID: 35296644 Free PMC article.
Establishing a safe anesthesia concentration window for Nile tilapia (Oreochromis niloticus) (Linnaeus 1758) by monitoring cardiac activity in eugenol immersion baths.
da Paz CA, da Costa BMPA, Hamoy MKO, Dos Santos MF, da Rocha LL, da Silva Deiga Y, de Sousa Barbosa A, do Amaral ALG, Câmara TM, Barbosa GB, de Araujo DB, Hartcopff PFP, Barbas LAL, Muto NA, Hamoy M. da Paz CA, et al. Among authors: da costa bmpa. Comp Biochem Physiol C Toxicol Pharmacol. 2024 Apr;278:109839. doi: 10.1016/j.cbpc.2024.109839. Epub 2024 Jan 11. Comp Biochem Physiol C Toxicol Pharmacol. 2024. PMID: 38218568
Evaluation of the Risk of Clinical Deterioration among Inpatients with COVID-19.
Costa VO, Nicolini EM, da Costa BMA, Teixeira FM, Ferreira JP, Moura MA, Montessi J, Campos RL, Guaraldo AN, Costa PM. Costa VO, et al. Among authors: da costa bma. Adv Virol. 2021 Jun 25;2021:6689669. doi: 10.1155/2021/6689669. eCollection 2021. Adv Virol. 2021. PMID: 34257657 Free PMC article.
20 results