Altered cytokine production in mice lacking P2X(7) receptors.
J Biol Chem. 2001.
PMID: 11016935
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Altered cytokine production in mice lacking P2X(7) receptors.
Solle M, Labasi J, Perregaux DG, Stam E, Petrushova N, Koller BH, Griffiths RJ, Gabel CA.
Solle M, et al.
J Biol Chem. 2001 Jan 5;276(1):125-32. doi: 10.1074/jbc.M006781200.
J Biol Chem. 2001.
PMID: 11016935
Free article.
The P2X(7) receptor (P2X(7)R) is an ATP-gated ion channel expressed by monocytes and macrophages. To directly address the role of this receptor in interleukin (IL)-1 beta post-translational processing, we have generated a P2X(7)R-deficient mouse line. ...
The P2X(7) receptor (P2X(7)R) is an ATP-gated ion channel expressed by monocytes and macrophages. To directly address the role of thi …
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ATP and the purine type 2 X7 receptor affect sleep.
Krueger JM, Taishi P, De A, Davis CJ, Winters BD, Clinton J, Szentirmai E, Zielinski MR.
Krueger JM, et al.
J Appl Physiol (1985). 2010 Nov;109(5):1318-27. doi: 10.1152/japplphysiol.00586.2010. Epub 2010 Sep 9.
J Appl Physiol (1985). 2010.
PMID: 20829501
Free PMC article.
Rat P2X7 receptor protein varied in the somatosensory cortex with time of day, and P2X7 mRNA was altered by interleukin-1 treatment, by sleep deprivation, and with time of day in the hypothalamus and somatosensory cortex. Mice lacking fun …
Rat P2X7 receptor protein varied in the somatosensory cortex with time of day, and P2X7 mRNA was altered by inte …
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Lack of a Functioning P2X7 Receptor Leads to Increased Susceptibility to Toxoplasmic Ileitis.
Miller CM, Zakrzewski AM, Robinson DP, Fuller SJ, Walker RA, Ikin RJ, Bao SJ, Grigg ME, Wiley JS, Smith NC.
Miller CM, et al.
PLoS One. 2015 Jun 8;10(6):e0129048. doi: 10.1371/journal.pone.0129048. eCollection 2015.
PLoS One. 2015.
PMID: 26053862
Free PMC article.
PRINCIPAL FINDINGS: Mice lacking the purinergic receptor P2X7R are acutely susceptible to toxoplasmic ileitis, losing significantly more weight than C57BL/6J mice and exhibiting much greater intestinal inflammatory pathology in response to infection wi …
PRINCIPAL FINDINGS: Mice lacking the purinergic receptor P2X7R are acutely susceptible to toxoplasmic ileitis, losing s …
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