Zuo E - Search Results

1

THEMIS is a substrate and allosteric activator of SHP1, playing dual roles during T cell development.

Zhang J, Jiang Z, Zhang X, Yang Z, Wang J, Chen J, Chen L, Song M, Zhang Y, Huang M, Chen S, Xiong X, Wang Y, Hao P, Horng T, Zhuang M, Zhang L, Zuo E, Bai F, Zheng J, Wang H, Fan G. Zhang J, et al. Among authors: zuo e. Nat Struct Mol Biol. 2024 Jan;31(1):54-67. doi: 10.1038/s41594-023-01131-3. Epub 2024 Jan 4. Nat Struct Mol Biol. 2024. PMID: 38177672

2

Off-target RNA mutation induced by DNA base editing and its elimination by mutagenesis.

Zhou C, Sun Y, Yan R, Liu Y, Zuo E, Gu C, Han L, Wei Y, Hu X, Zeng R, Li Y, Zhou H, Guo F, Yang H. Zhou C, et al. Among authors: zuo e. Nature. 2019 Jul;571(7764):275-278. doi: 10.1038/s41586-019-1314-0. Epub 2019 Jun 10. Nature. 2019. PMID: 31181567

3

A rationally engineered cytosine base editor retains high on-target activity while reducing both DNA and RNA off-target effects.

Zuo E, Sun Y, Yuan T, He B, Zhou C, Ying W, Liu J, Wei W, Zeng R, Li Y, Yang H. Zuo E, et al. Nat Methods. 2020 Jun;17(6):600-604. doi: 10.1038/s41592-020-0832-x. Epub 2020 May 18. Nat Methods. 2020. PMID: 32424272

4

EpiCas-DL: Predicting sgRNA activity for CRISPR-mediated epigenome editing by deep learning.

Yang Q, Wu L, Meng J, Ma L, Zuo E, Sun Y. Yang Q, et al. Among authors: zuo e. Comput Struct Biotechnol J. 2022 Nov 19;21:202-211. doi: 10.1016/j.csbj.2022.11.034. eCollection 2023. Comput Struct Biotechnol J. 2022. PMID: 36582444 Free PMC article.

5

Cytosine base editors induce off-target mutations and adverse phenotypic effects in transgenic mice.

Yan N, Feng H, Sun Y, Xin Y, Zhang H, Lu H, Zheng J, He C, Zuo Z, Yuan T, Li N, Xie L, Wei W, Sun Y, Zuo E. Yan N, et al. Among authors: zuo z, zuo e. Nat Commun. 2023 Mar 30;14(1):1784. doi: 10.1038/s41467-023-37508-7. Nat Commun. 2023. PMID: 36997536 Free PMC article.

6

GOTI, a method to identify genome-wide off-target effects of genome editing in mouse embryos.

Zuo E, Sun Y, Wei W, Yuan T, Ying W, Sun H, Yuan L, Steinmetz LM, Li Y, Yang H. Zuo E, et al. Nat Protoc. 2020 Sep;15(9):3009-3029. doi: 10.1038/s41596-020-0361-1. Epub 2020 Aug 14. Nat Protoc. 2020. PMID: 32796939 Free PMC article.

7

Optimization of C-to-G base editors with sequence context preference predictable by machine learning methods.

Yuan T, Yan N, Fei T, Zheng J, Meng J, Li N, Liu J, Zhang H, Xie L, Ying W, Li D, Shi L, Sun Y, Li Y, Li Y, Sun Y, Zuo E. Yuan T, et al. Among authors: zuo e. Nat Commun. 2021 Aug 12;12(1):4902. doi: 10.1038/s41467-021-25217-y. Nat Commun. 2021. PMID: 34385461 Free PMC article.

8

Genome-wide CRISPR off-target prediction and optimization using RNA-DNA interaction fingerprints.

Chen Q, Chuai G, Zhang H, Tang J, Duan L, Guan H, Li W, Li W, Wen J, Zuo E, Zhang Q, Liu Q. Chen Q, et al. Among authors: zuo e. Nat Commun. 2023 Nov 18;14(1):7521. doi: 10.1038/s41467-023-42695-4. Nat Commun. 2023. PMID: 37980345 Free PMC article.

9

CRISPR-Cas9-mediated genome editing in one blastomere of two-cell embryos reveals a novel Tet3 function in regulating neocortical development.

Wang L, Li MY, Qu C, Miao WY, Yin Q, Liao J, Cao HT, Huang M, Wang K, Zuo E, Peng G, Zhang SX, Chen G, Li Q, Tang K, Yu Q, Li Z, Wong CC, Xu G, Jing N, Yu X, Li J. Wang L, et al. Among authors: zuo e. Cell Res. 2017 Jun;27(6):815-829. doi: 10.1038/cr.2017.58. Epub 2017 Apr 21. Cell Res. 2017. PMID: 28429771 Free PMC article.

10

CRISPR/Cas9-mediated targeted chromosome elimination.

Zuo E, Huo X, Yao X, Hu X, Sun Y, Yin J, He B, Wang X, Shi L, Ping J, Wei Y, Ying W, Wei W, Liu W, Tang C, Li Y, Hu J, Yang H. Zuo E, et al. Genome Biol. 2017 Nov 24;18(1):224. doi: 10.1186/s13059-017-1354-4. Genome Biol. 2017. PMID: 29178945 Free PMC article.

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