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Activation of JAK/STAT3 restores NK-cell function and improves immune defense after brain ischemia.
Jin WN, Ducruet AF, Liu Q, Shi SX, Waters M, Zou M, Sheth KN, Gonzales R, Shi FD. Jin WN, et al. Among authors: zou m. FASEB J. 2018 May;32(5):2757-2767. doi: 10.1096/fj.201700962R. Epub 2018 Jan 8. FASEB J. 2018. PMID: 29401578 Free PMC article.
Our data suggest that brain ischemia impairs NK-cell-mediated immune defense in the periphery, at least in part through the JAK-STAT3 pathway, which can be readdressed by modulating STAT3 activation status.-Jin, W.-N., Ducruet, A. F., Liu, Q., Shi, S. X.-Y., Waters, M., …
Our data suggest that brain ischemia impairs NK-cell-mediated immune defense in the periphery, at least in part through the JAK-STAT3 pathwa …
Effect of Argatroban Plus Intravenous Alteplase vs Intravenous Alteplase Alone on Neurologic Function in Patients With Acute Ischemic Stroke: The ARAIS Randomized Clinical Trial.
Chen HS, Cui Y, Zhou ZH, Dai YJ, Li GH, Peng ZL, Zhang Y, Liu XD, Yuan ZM, Jiang CH, Yang QC, Duan YJ, Ma GB, Zhao LW, Wang RX, Sun YL, Shen L, Wang EQ, Wang LH, Feng YF, Wang FY, Zou RL, Yang HP, Wang K, Wang DL, Wang YL; ARAIS Investigators. Chen HS, et al. JAMA. 2023 Feb 28;329(8):640-650. doi: 10.1001/jama.2023.0550. JAMA. 2023. PMID: 36757755 Free PMC article. Clinical Trial.
2,213 results