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Activating KRAS, NRAS, and BRAF mutants enhance proteasome capacity and reduce endoplasmic reticulum stress in multiple myeloma.
Shirazi F, Jones RJ, Singh RK, Zou J, Kuiatse I, Berkova Z, Wang H, Lee HC, Hong S, Dick L, Chattopadhyay N, Orlowski RZ. Shirazi F, et al. Among authors: zou j. Proc Natl Acad Sci U S A. 2020 Aug 18;117(33):20004-20014. doi: 10.1073/pnas.2005052117. Epub 2020 Aug 3. Proc Natl Acad Sci U S A. 2020. PMID: 32747568 Free PMC article.
The novel protein homeostatic modulator BTX306 is active in myeloma and overcomes bortezomib and lenalidomide resistance.
Zou J, Jones RJ, Wang H, Kuiatse I, Shirazi F, Manasanch EE, Lee HC, Sullivan R, Fung L, Richard N, Erdman P, Torres E, Hecht D, Lam I, McElwee B, Chourasia AH, Chan KWH, Mercurio F, Stirling DI, Orlowski RZ. Zou J, et al. J Mol Med (Berl). 2020 Aug;98(8):1161-1173. doi: 10.1007/s00109-020-01943-6. Epub 2020 Jul 6. J Mol Med (Berl). 2020. PMID: 32632752 Free PMC article.
Structural insights into drug transport by an aquaglyceroporin.
Chen W, Zou R, Mei Y, Li J, Xuan Y, Cui B, Zou J, Wang J, Lin S, Zhang Z, Wang C. Chen W, et al. Among authors: zou j. Nat Commun. 2024 May 11;15(1):3985. doi: 10.1038/s41467-024-48445-4. Nat Commun. 2024. PMID: 38734677 Free PMC article.
Perivascular neurons instruct 3D vascular lattice formation via neurovascular contact.
Toma K, Zhao M, Zhang S, Wang F, Graham HK, Zou J, Modgil S, Shang WH, Tsai NY, Cai Z, Liu L, Hong G, Kriegstein AR, Hu Y, Körbelin J, Zhang R, Liao YJ, Kim TN, Ye X, Duan X. Toma K, et al. Among authors: zou j. Cell. 2024 May 6:S0092-8674(24)00405-7. doi: 10.1016/j.cell.2024.04.010. Online ahead of print. Cell. 2024. PMID: 38733989
7,652 results