Zlokovic BV - Search Results

1

A multimodal RAGE-specific inhibitor reduces amyloid β-mediated brain disorder in a mouse model of Alzheimer disease.

Deane R, Singh I, Sagare AP, Bell RD, Ross NT, LaRue B, Love R, Perry S, Paquette N, Deane RJ, Thiyagarajan M, Zarcone T, Fritz G, Friedman AE, Miller BL, Zlokovic BV. Deane R, et al. Among authors: zlokovic bv. J Clin Invest. 2012 Apr;122(4):1377-92. doi: 10.1172/JCI58642. Epub 2012 Mar 12. J Clin Invest. 2012. PMID: 22406537 Free PMC article.

2

Human blood-brain barrier receptors for Alzheimer's amyloid-beta 1- 40. Asymmetrical binding, endocytosis, and transcytosis at the apical side of brain microvascular endothelial cell monolayer.

Mackic JB, Stins M, McComb JG, Calero M, Ghiso J, Kim KS, Yan SD, Stern D, Schmidt AM, Frangione B, Zlokovic BV. Mackic JB, et al. Among authors: zlokovic bv. J Clin Invest. 1998 Aug 15;102(4):734-43. doi: 10.1172/JCI2029. J Clin Invest. 1998. PMID: 9710442 Free PMC article.

3

Clearance of Alzheimer's amyloid-ss(1-40) peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier.

Shibata M, Yamada S, Kumar SR, Calero M, Bading J, Frangione B, Holtzman DM, Miller CA, Strickland DK, Ghiso J, Zlokovic BV. Shibata M, et al. Among authors: zlokovic bv. J Clin Invest. 2000 Dec;106(12):1489-99. doi: 10.1172/JCI10498. J Clin Invest. 2000. PMID: 11120756 Free PMC article.

4

RAGE mediates amyloid-beta peptide transport across the blood-brain barrier and accumulation in brain.

Deane R, Du Yan S, Submamaryan RK, LaRue B, Jovanovic S, Hogg E, Welch D, Manness L, Lin C, Yu J, Zhu H, Ghiso J, Frangione B, Stern A, Schmidt AM, Armstrong DL, Arnold B, Liliensiek B, Nawroth P, Hofman F, Kindy M, Stern D, Zlokovic B. Deane R, et al. Nat Med. 2003 Jul;9(7):907-13. doi: 10.1038/nm890. Nat Med. 2003. PMID: 12808450

5

Brain capillary endothelium and choroid plexus epithelium regulate transport of transferrin-bound and free iron into the rat brain.

Deane R, Zheng W, Zlokovic BV. Deane R, et al. Among authors: zlokovic bv. J Neurochem. 2004 Feb;88(4):813-20. doi: 10.1046/j.1471-4159.2003.02221.x. J Neurochem. 2004. PMID: 14756801 Free PMC article.

6

Early-onset and robust cerebral microvascular accumulation of amyloid beta-protein in transgenic mice expressing low levels of a vasculotropic Dutch/Iowa mutant form of amyloid beta-protein precursor.

Davis J, Xu F, Deane R, Romanov G, Previti ML, Zeigler K, Zlokovic BV, Van Nostrand WE. Davis J, et al. Among authors: zlokovic bv. J Biol Chem. 2004 May 7;279(19):20296-306. doi: 10.1074/jbc.M312946200. Epub 2004 Feb 25. J Biol Chem. 2004. PMID: 14985348 Free article.

7

Clearing amyloid through the blood-brain barrier.

Zlokovic BV. Zlokovic BV. J Neurochem. 2004 May;89(4):807-11. doi: 10.1111/j.1471-4159.2004.02385.x. J Neurochem. 2004. PMID: 15140180 Free article. Review.

8

LRP/amyloid beta-peptide interaction mediates differential brain efflux of Abeta isoforms.

Deane R, Wu Z, Sagare A, Davis J, Du Yan S, Hamm K, Xu F, Parisi M, LaRue B, Hu HW, Spijkers P, Guo H, Song X, Lenting PJ, Van Nostrand WE, Zlokovic BV. Deane R, et al. Among authors: zlokovic bv. Neuron. 2004 Aug 5;43(3):333-44. doi: 10.1016/j.neuron.2004.07.017. Neuron. 2004. PMID: 15294142 Free article.

9

Method for measurement of the blood-brain barrier permeability in the perfused mouse brain: application to amyloid-beta peptide in wild type and Alzheimer's Tg2576 mice.

LaRue B, Hogg E, Sagare A, Jovanovic S, Maness L, Maurer C, Deane R, Zlokovic BV. LaRue B, et al. Among authors: zlokovic bv. J Neurosci Methods. 2004 Sep 30;138(1-2):233-42. doi: 10.1016/j.jneumeth.2004.04.026. J Neurosci Methods. 2004. PMID: 15325132

10

RAGE (yin) versus LRP (yang) balance regulates alzheimer amyloid beta-peptide clearance through transport across the blood-brain barrier.

Deane R, Wu Z, Zlokovic BV. Deane R, et al. Among authors: zlokovic bv. Stroke. 2004 Nov;35(11 Suppl 1):2628-31. doi: 10.1161/01.STR.0000143452.85382.d1. Epub 2004 Sep 30. Stroke. 2004. PMID: 15459432

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