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SETD5 haploinsufficiency affects mitochondrial compartment in neural cells.
Zaghi M, Longo F, Massimino L, Rubio A, Bido S, Mazzara PG, Bellini E, Banfi F, Podini P, Maltecca F, Zippo A, Broccoli V, Sessa A. Zaghi M, et al. Among authors: zippo a. Mol Autism. 2023 Jun 1;14(1):20. doi: 10.1186/s13229-023-00550-9. Mol Autism. 2023. PMID: 37264456 Free PMC article.
SETD5 Regulates Chromatin Methylation State and Preserves Global Transcriptional Fidelity during Brain Development and Neuronal Wiring.
Sessa A, Fagnocchi L, Mastrototaro G, Massimino L, Zaghi M, Indrigo M, Cattaneo S, Martini D, Gabellini C, Pucci C, Fasciani A, Belli R, Taverna S, Andreazzoli M, Zippo A, Broccoli V. Sessa A, et al. Among authors: zippo a. Neuron. 2019 Oct 23;104(2):271-289.e13. doi: 10.1016/j.neuron.2019.07.013. Epub 2019 Sep 9. Neuron. 2019. PMID: 31515109 Free article.
Aberrant L-Fucose Accumulation and Increased Core Fucosylation Are Metabolic Liabilities in Mesenchymal Glioblastoma.
Pieri V, Gallotti AL, Drago D, Cominelli M, Pagano I, Conti V, Valtorta S, Coliva A, Lago S, Michelatti D, Massimino L, Ungaro F, Perani L, Spinelli A, Castellano A, Falini A, Zippo A, Poliani PL, Moresco RM, Andolfo A, Galli R. Pieri V, et al. Among authors: zippo a. Cancer Res. 2023 Jan 18;83(2):195-218. doi: 10.1158/0008-5472.CAN-22-0677. Cancer Res. 2023. PMID: 36409826
MLL4-associated condensates counterbalance Polycomb-mediated nuclear mechanical stress in Kabuki syndrome.
Fasciani A, D'Annunzio S, Poli V, Fagnocchi L, Beyes S, Michelatti D, Corazza F, Antonelli L, Gregoretti F, Oliva G, Belli R, Peroni D, Domenici E, Zambrano S, Intartaglia D, Settembre C, Conte I, Testi C, Vergyris P, Ruocco G, Zippo A. Fasciani A, et al. Among authors: zippo a. Nat Genet. 2020 Dec;52(12):1397-1411. doi: 10.1038/s41588-020-00724-8. Epub 2020 Nov 9. Nat Genet. 2020. PMID: 33169020 Free PMC article.
mTORC1 promotes malignant large cell/anaplastic histology and is a targetable vulnerability in SHH-TP53 mutant medulloblastoma.
Conti V, Cominelli M, Pieri V, Gallotti AL, Pagano I, Zanella M, Mazzoleni S, Pivetta F, Patanè M, Scotti GM, Piras IS, Pollo B, Falini A, Zippo A, Castellano A, Maestro R, Poliani PL, Galli R. Conti V, et al. Among authors: zippo a. JCI Insight. 2021 Dec 8;6(23):e153462. doi: 10.1172/jci.insight.153462. JCI Insight. 2021. PMID: 34673573 Free PMC article.
58 results