Zimmerli SC - Search Results

1

Efficacy and Pharmacodynamic Modeling of the BTK Inhibitor Evobrutinib in Autoimmune Disease Models.

Haselmayer P, Camps M, Liu-Bujalski L, Nguyen N, Morandi F, Head J, O'Mahony A, Zimmerli SC, Bruns L, Bender AT, Schroeder P, Grenningloh R. Haselmayer P, et al. Among authors: zimmerli sc. J Immunol. 2019 May 15;202(10):2888-2906. doi: 10.4049/jimmunol.1800583. Epub 2019 Apr 15. J Immunol. 2019. PMID: 30988116 Free PMC article.

2

Discovery of Evobrutinib: An Oral, Potent, and Highly Selective, Covalent Bruton's Tyrosine Kinase (BTK) Inhibitor for the Treatment of Immunological Diseases.

Caldwell RD, Qiu H, Askew BC, Bender AT, Brugger N, Camps M, Dhanabal M, Dutt V, Eichhorn T, Gardberg AS, Goutopoulos A, Grenningloh R, Head J, Healey B, Hodous BL, Huck BR, Johnson TL, Jones C, Jones RC, Mochalkin I, Morandi F, Nguyen N, Meyring M, Potnick JR, Santos DC, Schmidt R, Sherer B, Shutes A, Urbahns K, Follis AV, Wegener AA, Zimmerli SC, Liu-Bujalski L. Caldwell RD, et al. Among authors: zimmerli sc. J Med Chem. 2019 Sep 12;62(17):7643-7655. doi: 10.1021/acs.jmedchem.9b00794. Epub 2019 Aug 15. J Med Chem. 2019. PMID: 31368705

3

Discovery of M5049: A Novel Selective Toll-Like Receptor 7/8 Inhibitor for Treatment of Autoimmunity.

Vlach J, Bender AT, Przetak M, Pereira A, Deshpande A, Johnson TL, Reissig S, Tzvetkov E, Musil D, Morse NT, Haselmayer P, Zimmerli SC, Okitsu SL, Walsky RL, Sherer B. Vlach J, et al. Among authors: zimmerli sc. J Pharmacol Exp Ther. 2021 Mar;376(3):397-409. doi: 10.1124/jpet.120.000275. Epub 2020 Dec 16. J Pharmacol Exp Ther. 2021. PMID: 33328334

4

Dibutyl phthalate-induced thymic stromal lymphopoietin is required for Th2 contact hypersensitivity responses.

Larson RP, Zimmerli SC, Comeau MR, Itano A, Omori M, Iseki M, Hauser C, Ziegler SF. Larson RP, et al. Among authors: zimmerli sc. J Immunol. 2010 Mar 15;184(6):2974-84. doi: 10.4049/jimmunol.0803478. Epub 2010 Feb 19. J Immunol. 2010. PMID: 20173025 Free PMC article.

5

Cutting edge: Lack of evidence for connexin-43 expression in human epidermal Langerhans cells.

Zimmerli SC, Masson F, Cancela J, Meda P, Hauser C. Zimmerli SC, et al. J Immunol. 2007 Oct 1;179(7):4318-21. doi: 10.4049/jimmunol.179.7.4318. J Immunol. 2007. PMID: 17878326

6

Food allergy in mice is modulated through the thymic stromal lymphopoietin pathway.

Frossard CP, Zimmerli SC, Rincon Garriz JM, Eigenmann PA. Frossard CP, et al. Among authors: zimmerli sc. Clin Transl Allergy. 2016 Jan 19;6:2. doi: 10.1186/s13601-016-0090-2. eCollection 2015. Clin Transl Allergy. 2016. PMID: 26793299 Free PMC article.

7

Discovery of potent, selective, and orally bioavailable alkynylphenoxyacetic acid CRTH2 (DP2) receptor antagonists for the treatment of allergic inflammatory diseases.

Crosignani S, Prêtre A, Jorand-Lebrun C, Fraboulet G, Seenisamy J, Augustine JK, Missotten M, Humbert Y, Cleva C, Abla N, Daff H, Schott O, Schneider M, Burgat-Charvillon F, Rivron D, Hamernig I, Arrighi JF, Gaudet M, Zimmerli SC, Juillard P, Johnson Z. Crosignani S, et al. Among authors: zimmerli sc. J Med Chem. 2011 Oct 27;54(20):7299-317. doi: 10.1021/jm200866y. Epub 2011 Oct 3. J Med Chem. 2011. PMID: 21916510

8

Langerhans cells and lymph node dendritic cells express the tight junction component claudin-1.

Zimmerli SC, Hauser C. Zimmerli SC, et al. J Invest Dermatol. 2007 Oct;127(10):2381-90. doi: 10.1038/sj.jid.5700882. Epub 2007 May 17. J Invest Dermatol. 2007. PMID: 17508021 Free article.

9

Human epidermal Langerhans cells express the tight junction protein claudin-1 and are present in human genetic claudin-1 deficiency (NISCH syndrome).

Zimmerli SC, Kerl K, Hadj-Rabia S, Hohl D, Hauser C. Zimmerli SC, et al. Exp Dermatol. 2008 Jan;17(1):20-3. doi: 10.1111/j.1600-0625.2007.00624.x. Exp Dermatol. 2008. PMID: 18095941

10

Protective effect of TSLP delivered at the gut mucosa level by recombinant lactic acid bacteria in DSS-induced colitis mouse model.

Aubry C, Michon C, Chain F, Chvatchenko Y, Goffin L, Zimmerli SC, Leguin S, Langella P, Bermudez-Humaran L, Chatel JM. Aubry C, et al. Among authors: zimmerli sc. Microb Cell Fact. 2015 Nov 6;14:176. doi: 10.1186/s12934-015-0367-5. Microb Cell Fact. 2015. PMID: 26546058 Free PMC article.

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