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Identification of DAXX as a restriction factor of SARS-CoV-2 through a CRISPR/Cas9 screen.
Mac Kain A, Maarifi G, Aicher SM, Arhel N, Baidaliuk A, Munier S, Donati F, Vallet T, Tran QD, Hardy A, Chazal M, Porrot F, OhAinle M, Carlson-Stevermer J, Oki J, Holden K, Zimmer G, Simon-Lorière E, Bruel T, Schwartz O, van der Werf S, Jouvenet N, Nisole S, Vignuzzi M, Roesch F. Mac Kain A, et al. Among authors: zimmer g. Nat Commun. 2022 May 4;13(1):2442. doi: 10.1038/s41467-022-30134-9. Nat Commun. 2022. PMID: 35508460 Free PMC article.
Within-host evolution of SARS-CoV-2 in an immunosuppressed COVID-19 patient as a source of immune escape variants.
Weigang S, Fuchs J, Zimmer G, Schnepf D, Kern L, Beer J, Luxenburger H, Ankerhold J, Falcone V, Kemming J, Hofmann M, Thimme R, Neumann-Haefelin C, Ulferts S, Grosse R, Hornuss D, Tanriver Y, Rieg S, Wagner D, Huzly D, Schwemmle M, Panning M, Kochs G. Weigang S, et al. Among authors: zimmer g. Nat Commun. 2021 Nov 4;12(1):6405. doi: 10.1038/s41467-021-26602-3. Nat Commun. 2021. PMID: 34737266 Free PMC article.
Species-Specific Molecular Barriers to SARS-CoV-2 Replication in Bat Cells.
Aicher SM, Streicher F, Chazal M, Planas D, Luo D, Buchrieser J, Nemcova M, Seidlova V, Zukal J, Serra-Cobo J, Pontier D, Pain B, Zimmer G, Schwartz O, Roingeard P, Pikula J, Dacheux L, Jouvenet N. Aicher SM, et al. Among authors: zimmer g. J Virol. 2022 Jul 27;96(14):e0060822. doi: 10.1128/jvi.00608-22. Epub 2022 Jul 5. J Virol. 2022. PMID: 35862713 Free PMC article.
MHC class II proteins mediate cross-species entry of bat influenza viruses.
Karakus U, Thamamongood T, Ciminski K, Ran W, Günther SC, Pohl MO, Eletto D, Jeney C, Hoffmann D, Reiche S, Schinköthe J, Ulrich R, Wiener J, Hayes MGB, Chang MW, Hunziker A, Yángüez E, Aydillo T, Krammer F, Oderbolz J, Meier M, Oxenius A, Halenius A, Zimmer G, Benner C, Hale BG, García-Sastre A, Beer M, Schwemmle M, Stertz S. Karakus U, et al. Among authors: zimmer g. Nature. 2019 Mar;567(7746):109-112. doi: 10.1038/s41586-019-0955-3. Epub 2019 Feb 20. Nature. 2019. PMID: 30787439
LY6E impairs coronavirus fusion and confers immune control of viral disease.
Pfaender S, Mar KB, Michailidis E, Kratzel A, Boys IN, V'kovski P, Fan W, Kelly JN, Hirt D, Ebert N, Stalder H, Kleine-Weber H, Hoffmann M, Hoffmann HH, Saeed M, Dijkman R, Steinmann E, Wight-Carter M, McDougal MB, Hanners NW, Pöhlmann S, Gallagher T, Todt D, Zimmer G, Rice CM, Schoggins JW, Thiel V. Pfaender S, et al. Among authors: zimmer g. Nat Microbiol. 2020 Nov;5(11):1330-1339. doi: 10.1038/s41564-020-0769-y. Epub 2020 Jul 23. Nat Microbiol. 2020. PMID: 32704094 Free PMC article.
A genome-wide CRISPR screen identifies interactors of the autophagy pathway as conserved coronavirus targets.
Kratzel A, Kelly JN, V'kovski P, Portmann J, Brüggemann Y, Todt D, Ebert N, Shrestha N, Plattet P, Staab-Weijnitz CA, von Brunn A, Steinmann E, Dijkman R, Zimmer G, Pfaender S, Thiel V. Kratzel A, et al. Among authors: zimmer g. PLoS Biol. 2021 Dec 28;19(12):e3001490. doi: 10.1371/journal.pbio.3001490. eCollection 2021 Dec. PLoS Biol. 2021. PMID: 34962926 Free PMC article.
Biparatopic sybodies neutralize SARS-CoV-2 variants of concern and mitigate drug resistance.
Walter JD, Scherer M, Hutter CAJ, Garaeva AA, Zimmermann I, Wyss M, Rheinberger J, Ruedin Y, Earp JC, Egloff P, Sorgenfrei M, Hürlimann LM, Gonda I, Meier G, Remm S, Thavarasah S, van Geest G, Bruggmann R, Zimmer G, Slotboom DJ, Paulino C, Plattet P, Seeger MA. Walter JD, et al. Among authors: zimmer g. EMBO Rep. 2022 Apr 5;23(4):e54199. doi: 10.15252/embr.202154199. Epub 2022 Mar 7. EMBO Rep. 2022. PMID: 35253970 Free PMC article.
Potent neutralization by monoclonal human IgM against SARS-CoV-2 is impaired by class switch.
Callegari I, Schneider M, Berloffa G, Mühlethaler T, Holdermann S, Galli E, Roloff T, Boss R, Infanti L, Khanna N, Egli A, Buser A, Zimmer G, Derfuss T, Sanderson NSR. Callegari I, et al. Among authors: zimmer g. EMBO Rep. 2022 Jul 5;23(7):e53956. doi: 10.15252/embr.202153956. Epub 2022 May 12. EMBO Rep. 2022. PMID: 35548920 Free PMC article.
332 results