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Targeting NAD+ in translational research to relieve diseases and conditions of metabolic stress and ageing.
Gilmour BC, Gudmundsrud R, Frank J, Hov A, Lautrup S, Aman Y, Røsjø H, Brenner C, Ziegler M, Tysnes OB, Tzoulis C, Omland T, Søraas A, Holmøy T, Bergersen LH, Storm-Mathisen J, Nilsen H, Fang EF. Gilmour BC, et al. Among authors: ziegler m. Mech Ageing Dev. 2020 Mar;186:111208. doi: 10.1016/j.mad.2020.111208. Epub 2020 Jan 15. Mech Ageing Dev. 2020. PMID: 31953124 Free article. Review.
NAD(+) biosynthesis and salvage--a phylogenetic perspective.
Gossmann TI, Ziegler M, Puntervoll P, de Figueiredo LF, Schuster S, Heiland I. Gossmann TI, et al. Among authors: ziegler m. FEBS J. 2012 Sep;279(18):3355-63. doi: 10.1111/j.1742-4658.2012.08559.x. Epub 2012 Apr 4. FEBS J. 2012. PMID: 22404877 Free article.
NAD and ADP-ribose metabolism in mitochondria.
Dölle C, Rack JG, Ziegler M. Dölle C, et al. Among authors: ziegler m. FEBS J. 2013 Aug;280(15):3530-41. doi: 10.1111/febs.12304. Epub 2013 Jun 3. FEBS J. 2013. PMID: 23617329 Free article. Review.
Disease-specific phenotypes in iPSC-derived neural stem cells with POLG mutations.
Liang KX, Kristiansen CK, Mostafavi S, Vatne GH, Zantingh GA, Kianian A, Tzoulis C, Høyland LE, Ziegler M, Perez RM, Furriol J, Zhang Z, Balafkan N, Hong Y, Siller R, Sullivan GJ, Bindoff LA. Liang KX, et al. Among authors: ziegler m. EMBO Mol Med. 2020 Oct 7;12(10):e12146. doi: 10.15252/emmm.202012146. Epub 2020 Aug 25. EMBO Mol Med. 2020. PMID: 32840960 Free PMC article.
The balance between NAD+ biosynthesis and consumption in ageing.
Strømland Ø, Diab J, Ferrario E, Sverkeli LJ, Ziegler M. Strømland Ø, et al. Among authors: ziegler m. Mech Ageing Dev. 2021 Oct;199:111569. doi: 10.1016/j.mad.2021.111569. Epub 2021 Sep 9. Mech Ageing Dev. 2021. PMID: 34509469 Free article. Review.
The NADPARK study: A randomized phase I trial of nicotinamide riboside supplementation in Parkinson's disease.
Brakedal B, Dölle C, Riemer F, Ma Y, Nido GS, Skeie GO, Craven AR, Schwarzlmüller T, Brekke N, Diab J, Sverkeli L, Skjeie V, Varhaug K, Tysnes OB, Peng S, Haugarvoll K, Ziegler M, Grüner R, Eidelberg D, Tzoulis C. Brakedal B, et al. Among authors: ziegler m. Cell Metab. 2022 Mar 1;34(3):396-407.e6. doi: 10.1016/j.cmet.2022.02.001. Cell Metab. 2022. PMID: 35235774 Free article. Clinical Trial.
The NAD metabolome--a key determinant of cancer cell biology.
Chiarugi A, Dölle C, Felici R, Ziegler M. Chiarugi A, et al. Among authors: ziegler m. Nat Rev Cancer. 2012 Nov;12(11):741-52. doi: 10.1038/nrc3340. Epub 2012 Sep 28. Nat Rev Cancer. 2012. PMID: 23018234 Review.
1,794 results