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Conformational Heterogeneity and Cooperative Effects of Mammalian ALOX15.
Ivanov I, Cruz A, Zhuravlev A, Di Venere A, Nicolai E, Stehling S, Lluch JM, González-Lafont À, Kuhn H. Ivanov I, et al. Among authors: zhuravlev a. Int J Mol Sci. 2021 Mar 23;22(6):3285. doi: 10.3390/ijms22063285. Int J Mol Sci. 2021. PMID: 33807076 Free PMC article.
A role of Gln596 in fine-tuning mammalian ALOX15 specificity, protein stability and allosteric properties.
Cruz A, Di Venere A, Mei G, Zhuravlev A, Golovanov A, Stehling S, Heydeck D, Lluch JM, González-Lafont À, Kuhn H, Ivanov I. Cruz A, et al. Among authors: zhuravlev a. Biochim Biophys Acta Mol Cell Biol Lipids. 2020 Jul;1865(7):158680. doi: 10.1016/j.bbalip.2020.158680. Epub 2020 Mar 6. Biochim Biophys Acta Mol Cell Biol Lipids. 2020. PMID: 32151768
N-Substituted 5-(1H-Indol-2-yl)-2-methoxyanilines Are Allosteric Inhibitors of the Linoleate Oxygenase Activity of Selected Mammalian ALOX15 Orthologs: Mechanism of Action.
Golovanov A, Zhuravlev A, Cruz A, Aksenov V, Shafiullina R, Kakularam KR, Lluch JM, Kuhn H, González-Lafont À, Ivanov I. Golovanov A, et al. Among authors: zhuravlev a. J Med Chem. 2022 Feb 10;65(3):1979-1995. doi: 10.1021/acs.jmedchem.1c01563. Epub 2022 Jan 25. J Med Chem. 2022. PMID: 35073698
Different Structures-Similar Effect: Do Substituted 5-(4-Methoxyphenyl)-1H-indoles and 5-(4-Methoxyphenyl)-1H-imidazoles Represent a Common Pharmacophore for Substrate Selective Inhibition of Linoleate Oxygenase Activity of ALOX15?
Zhuravlev A, Cruz A, Aksenov V, Golovanov A, Lluch JM, Kuhn H, González-Lafont À, Ivanov I. Zhuravlev A, et al. Molecules. 2023 Jul 14;28(14):5418. doi: 10.3390/molecules28145418. Molecules. 2023. PMID: 37513289 Free PMC article.
Role of the mtDNA Mutations and Mitophagy in Inflammaging.
Dabravolski SA, Nikiforov NG, Zhuravlev AD, Orekhov NA, Grechko AV, Orekhov AN. Dabravolski SA, et al. Among authors: zhuravlev ad. Int J Mol Sci. 2022 Jan 25;23(3):1323. doi: 10.3390/ijms23031323. Int J Mol Sci. 2022. PMID: 35163247 Free PMC article. Review.
242 results