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Development and structural basis of a two-MAb cocktail for treating SARS-CoV-2 infections.
Zhang C, Wang Y, Zhu Y, Liu C, Gu C, Xu S, Wang Y, Zhou Y, Wang Y, Han W, Hong X, Yang Y, Zhang X, Wang T, Xu C, Hong Q, Wang S, Zhao Q, Qiao W, Zang J, Kong L, Wang F, Wang H, Qu D, Lavillette D, Tang H, Deng Q, Xie Y, Cong Y, Huang Z. Zhang C, et al. Among authors: zhu y. Nat Commun. 2021 Jan 11;12(1):264. doi: 10.1038/s41467-020-20465-w. Nat Commun. 2021. PMID: 33431876 Free PMC article.
A non-ACE2 competing human single-domain antibody confers broad neutralization against SARS-CoV-2 and circulating variants.
Yang Z, Wang Y, Jin Y, Zhu Y, Wu Y, Li C, Kong Y, Song W, Tian X, Zhan W, Huang A, Zhou S, Xia S, Tian X, Peng C, Chen C, Shi Y, Hu G, Du S, Wang Y, Xie Y, Jiang S, Lu L, Sun L, Song Y, Ying T. Yang Z, et al. Among authors: zhu y. Signal Transduct Target Ther. 2021 Nov 3;6(1):378. doi: 10.1038/s41392-021-00810-1. Signal Transduct Target Ther. 2021. PMID: 34732694 Free PMC article.
Mapping cross-variant neutralizing sites on the SARS-CoV-2 spike protein.
Xu S, Wang Y, Wang Y, Zhang C, Hong Q, Gu C, Xu R, Wang T, Yang Y, Zang J, Zhou Y, Li Z, Liu Q, Zhou B, Bai L, Zhu Y, Deng Q, Wang H, Lavillette D, Wong G, Xie Y, Cong Y, Huang Z. Xu S, et al. Among authors: zhu y. Emerg Microbes Infect. 2022 Dec;11(1):351-367. doi: 10.1080/22221751.2021.2024455. Emerg Microbes Infect. 2022. PMID: 34964428 Free PMC article.
Broad neutralization of SARS-CoV-2 variants by an inhalable bispecific single-domain antibody.
Li C, Zhan W, Yang Z, Tu C, Hu G, Zhang X, Song W, Du S, Zhu Y, Huang K, Kong Y, Zhang M, Mao Q, Gu X, Zhang Y, Xie Y, Deng Q, Song Y, Chen Z, Lu L, Jiang S, Wu Y, Sun L, Ying T. Li C, et al. Among authors: zhu y. Cell. 2022 Apr 14;185(8):1389-1401.e18. doi: 10.1016/j.cell.2022.03.009. Epub 2022 Mar 10. Cell. 2022. PMID: 35344711 Free PMC article.
Neutralization mechanism of a human antibody with pan-coronavirus reactivity including SARS-CoV-2.
Sun X, Yi C, Zhu Y, Ding L, Xia S, Chen X, Liu M, Gu C, Lu X, Fu Y, Chen S, Zhang T, Zhang Y, Yang Z, Ma L, Gu W, Hu G, Du S, Yan R, Fu W, Yuan S, Qiu C, Zhao C, Zhang X, He Y, Qu A, Zhou X, Li X, Wong G, Deng Q, Zhou Q, Lu H, Ling Z, Ding J, Lu L, Xu J, Xie Y, Sun B. Sun X, et al. Among authors: zhu y. Nat Microbiol. 2022 Jul;7(7):1063-1074. doi: 10.1038/s41564-022-01155-3. Epub 2022 Jun 30. Nat Microbiol. 2022. PMID: 35773398
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