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Hyperleptinemia contributes to antipsychotic drug-associated obesity and metabolic disorders.
Zhao S, Lin Q, Xiong W, Li L, Straub L, Zhang D, Zapata R, Zhu Q, Sun XN, Zhang Z, Funcke JB, Li C, Chen S, Zhu Y, Jiang N, Li G, Xu Z, Wyler SC, Wang MY, Bai J, Han X, Kusminski CM, Zhang N, An Z, Elmquist JK, Osborn O, Liu C, Scherer PE. Zhao S, et al. Among authors: zhu q, zhu y. Sci Transl Med. 2023 Nov 22;15(723):eade8460. doi: 10.1126/scitranslmed.ade8460. Epub 2023 Nov 22. Sci Transl Med. 2023. PMID: 37992151
Partial Leptin Reduction as an Insulin Sensitization and Weight Loss Strategy.
Zhao S, Zhu Y, Schultz RD, Li N, He Z, Zhang Z, Caron A, Zhu Q, Sun K, Xiong W, Deng H, Sun J, Deng Y, Kim M, Lee CE, Gordillo R, Liu T, Odle AK, Childs GV, Zhang N, Kusminski CM, Elmquist JK, Williams KW, An Z, Scherer PE. Zhao S, et al. Among authors: zhu q, zhu y. Cell Metab. 2019 Oct 1;30(4):706-719.e6. doi: 10.1016/j.cmet.2019.08.005. Epub 2019 Sep 5. Cell Metab. 2019. PMID: 31495688 Free PMC article.
Dermal adipose tissue has high plasticity and undergoes reversible dedifferentiation in mice.
Zhang Z, Shao M, Hepler C, Zi Z, Zhao S, An YA, Zhu Y, Ghaben AL, Wang MY, Li N, Onodera T, Joffin N, Crewe C, Zhu Q, Vishvanath L, Kumar A, Xing C, Wang QA, Gautron L, Deng Y, Gordillo R, Kruglikov I, Kusminski CM, Gupta RK, Scherer PE. Zhang Z, et al. Among authors: zhu q, zhu y. J Clin Invest. 2019 Dec 2;129(12):5327-5342. doi: 10.1172/JCI130239. J Clin Invest. 2019. PMID: 31503545 Free PMC article.
Suppressing adipocyte inflammation promotes insulin resistance in mice.
Zhu Q, An YA, Kim M, Zhang Z, Zhao S, Zhu Y, Asterholm IW, Kusminski CM, Scherer PE. Zhu Q, et al. Among authors: zhu y. Mol Metab. 2020 Sep;39:101010. doi: 10.1016/j.molmet.2020.101010. Epub 2020 May 11. Mol Metab. 2020. PMID: 32408016 Free PMC article.
Adiponectin preserves metabolic fitness during aging.
Li N, Zhao S, Zhang Z, Zhu Y, Gliniak CM, Vishvanath L, An YA, Wang MY, Deng Y, Zhu Q, Shan B, Sherwood A, Onodera T, Oz OK, Gordillo R, Gupta RK, Liu M, Horvath TL, Dixit VD, Scherer PE. Li N, et al. Among authors: zhu q, zhu y. Elife. 2021 Apr 27;10:e65108. doi: 10.7554/eLife.65108. Elife. 2021. PMID: 33904399 Free PMC article.
Adipocyte iron levels impinge on a fat-gut crosstalk to regulate intestinal lipid absorption and mediate protection from obesity.
Zhang Z, Funcke JB, Zi Z, Zhao S, Straub LG, Zhu Y, Zhu Q, Crewe C, An YA, Chen S, Li N, Wang MY, Ghaben AL, Lee C, Gautron L, Engelking LJ, Raj P, Deng Y, Gordillo R, Kusminski CM, Scherer PE. Zhang Z, et al. Among authors: zhu q, zhu y. Cell Metab. 2021 Aug 3;33(8):1624-1639.e9. doi: 10.1016/j.cmet.2021.06.001. Epub 2021 Jun 25. Cell Metab. 2021. PMID: 34174197 Free PMC article.
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