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Loss of phosphatase CTDNEP1 potentiates aggressive medulloblastoma by triggering MYC amplification and genomic instability.
Luo Z, Xin D, Liao Y, Berry K, Ogurek S, Zhang F, Zhang L, Zhao C, Rao R, Dong X, Li H, Yu J, Lin Y, Huang G, Xu L, Xin M, Nishinakamura R, Yu J, Kool M, Pfister SM, Roussel MF, Zhou W, Weiss WA, Andreassen P, Lu QR. Luo Z, et al. Among authors: zhou w. Nat Commun. 2023 Feb 10;14(1):762. doi: 10.1038/s41467-023-36400-8. Nat Commun. 2023. PMID: 36765089 Free PMC article.
The G protein α subunit Gαs is a tumor suppressor in Sonic hedgehog-driven medulloblastoma.
He X, Zhang L, Chen Y, Remke M, Shih D, Lu F, Wang H, Deng Y, Yu Y, Xia Y, Wu X, Ramaswamy V, Hu T, Wang F, Zhou W, Burns DK, Kim SH, Kool M, Pfister SM, Weinstein LS, Pomeroy SL, Gilbertson RJ, Rubin JB, Hou Y, Wechsler-Reya R, Taylor MD, Lu QR. He X, et al. Among authors: zhou w. Nat Med. 2014 Sep;20(9):1035-42. doi: 10.1038/nm.3666. Epub 2014 Aug 24. Nat Med. 2014. PMID: 25150496 Free PMC article.
Autism-like behaviours and germline transmission in transgenic monkeys overexpressing MeCP2.
Liu Z, Li X, Zhang JT, Cai YJ, Cheng TL, Cheng C, Wang Y, Zhang CC, Nie YH, Chen ZF, Bian WJ, Zhang L, Xiao J, Lu B, Zhang YF, Zhang XD, Sang X, Wu JJ, Xu X, Xiong ZQ, Zhang F, Yu X, Gong N, Zhou WH, Sun Q, Qiu Z. Liu Z, et al. Nature. 2016 Feb 4;530(7588):98-102. doi: 10.1038/nature16533. Epub 2016 Jan 25. Nature. 2016. PMID: 26808898
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