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A local tumor microenvironment acquired super-enhancer induces an oncogenic driver in colorectal carcinoma.
Zhou RW, Xu J, Martin TC, Zachem AL, He J, Ozturk S, Demircioglu D, Bansal A, Trotta AP, Giotti B, Gryder B, Shen Y, Wu X, Carcamo S, Bosch K, Hopkins B, Tsankov A, Steinhagen R, Jones DR, Asara J, Chipuk JE, Brody R, Itzkowitz S, Chio IIC, Hasson D, Bernstein E, Parsons RE. Zhou RW, et al. Nat Commun. 2022 Oct 17;13(1):6041. doi: 10.1038/s41467-022-33377-8. Nat Commun. 2022. PMID: 36253360 Free PMC article.
Leflunomide triggers synthetic lethality in PTEN-deficient prostate cancer.
Ozturk S, Mathur D, Zhou RW, Mulholland D, Parsons R. Ozturk S, et al. Among authors: zhou rw. Prostate Cancer Prostatic Dis. 2020 Dec;23(4):718-723. doi: 10.1038/s41391-020-0251-1. Epub 2020 Jul 13. Prostate Cancer Prostatic Dis. 2020. PMID: 32661432 Free PMC article.
AKT Degradation Selectively Inhibits the Growth of PI3K/PTEN Pathway-Mutant Cancers with Wild-Type KRAS and BRAF by Destabilizing Aurora Kinase B.
Xu J, Yu X, Martin TC, Bansal A, Cheung K, Lubin A, Stratikopoulos E, Cahuzac KM, Wang L, Xie L, Zhou R, Shen Y, Wu X, Yao S, Qiao R, Poulikakos PI, Chen X, Liu J, Jin J, Parsons R. Xu J, et al. Cancer Discov. 2021 Dec 1;11(12):3064-3089. doi: 10.1158/2159-8290.CD-20-0815. Cancer Discov. 2021. PMID: 34301793 Free PMC article.
Author Correction: A local tumor microenvironment acquired super-enhancer induces an oncogenic driver in colorectal carcinoma.
Zhou RW, Xu J, Martin TC, Zachem AL, He J, Ozturk S, Demircioglu D, Bansal A, Trotta AP, Giotti B, Gryder B, Shen Y, Wu X, Carcamo S, Bosch K, Hopkins B, Tsankov A, Steinhagen R, Jones DR, Asara J, Chipuk JE, Brody R, Itzkowitz S, Chio IIC, Hasson D, Bernstein E, Parsons RE. Zhou RW, et al. Nat Commun. 2023 Apr 6;14(1):1923. doi: 10.1038/s41467-023-37640-4. Nat Commun. 2023. PMID: 37024505 Free PMC article. No abstract available.
32 results