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Leveraging base-pair mammalian constraint to understand genetic variation and human disease.
Sullivan PF, Meadows JRS, Gazal S, Phan BN, Li X, Genereux DP, Dong MX, Bianchi M, Andrews G, Sakthikumar S, Nordin J, Roy A, Christmas MJ, Marinescu VD, Wang C, Wallerman O, Xue J, Yao S, Sun Q, Szatkiewicz J, Wen J, Huckins LM, Lawler A, Keough KC, Zheng Z, Zeng J, Wray NR, Li Y, Johnson J, Chen J; Zoonomia Consortium§; Paten B, Reilly SK, Hughes GM, Weng Z, Pollard KS, Pfenning AR, Forsberg-Nilsson K, Karlsson EK, Lindblad-Toh K. Sullivan PF, et al. Among authors: zheng z. Science. 2023 Apr 28;380(6643):eabn2937. doi: 10.1126/science.abn2937. Epub 2023 Apr 28. Science. 2023. PMID: 37104612 Free PMC article.
Genetic signatures of high-altitude adaptation in Tibetans.
Yang J, Jin ZB, Chen J, Huang XF, Li XM, Liang YB, Mao JY, Chen X, Zheng Z, Bakshi A, Zheng DD, Zheng MQ, Wray NR, Visscher PM, Lu F, Qu J. Yang J, et al. Among authors: zheng z, zheng mq, zheng dd. Proc Natl Acad Sci U S A. 2017 Apr 18;114(16):4189-4194. doi: 10.1073/pnas.1617042114. Epub 2017 Apr 3. Proc Natl Acad Sci U S A. 2017. PMID: 28373541 Free PMC article.
Improved polygenic prediction by Bayesian multiple regression on summary statistics.
Lloyd-Jones LR, Zeng J, Sidorenko J, Yengo L, Moser G, Kemper KE, Wang H, Zheng Z, Magi R, Esko T, Metspalu A, Wray NR, Goddard ME, Yang J, Visscher PM. Lloyd-Jones LR, et al. Among authors: zheng z. Nat Commun. 2019 Nov 8;10(1):5086. doi: 10.1038/s41467-019-12653-0. Nat Commun. 2019. PMID: 31704910 Free PMC article.
13,504 results
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