Zheng Y - Search Results

1

Ligand activation mechanisms of human KCNQ2 channel.

Ma D, Zheng Y, Li X, Zhou X, Yang Z, Zhang Y, Wang L, Zhang W, Fang J, Zhao G, Hou P, Nan F, Yang W, Su N, Gao Z, Guo J. Ma D, et al. Among authors: zheng y. Nat Commun. 2023 Oct 19;14(1):6632. doi: 10.1038/s41467-023-42416-x. Nat Commun. 2023. PMID: 37857637 Free PMC article.

2

Hexachlorophene is a potent KCNQ1/KCNE1 potassium channel activator which rescues LQTs mutants.

Zheng Y, Zhu X, Zhou P, Lan X, Xu H, Li M, Gao Z. Zheng Y, et al. PLoS One. 2012;7(12):e51820. doi: 10.1371/journal.pone.0051820. Epub 2012 Dec 12. PLoS One. 2012. PMID: 23251633 Free PMC article.

3

The human ether-a-go-go-related gene activator NS1643 enhances epilepsy-associated KCNQ channels.

Li P, Chen X, Zhang Q, Zheng Y, Jiang H, Yang H, Gao Z. Li P, et al. Among authors: zheng y. J Pharmacol Exp Ther. 2014 Dec;351(3):596-604. doi: 10.1124/jpet.114.217703. Epub 2014 Sep 17. J Pharmacol Exp Ther. 2014. PMID: 25232191

4

Activation of peripheral KCNQ channels relieves gout pain.

Zheng Y, Xu H, Zhan L, Zhou X, Chen X, Gao Z. Zheng Y, et al. Pain. 2015 Jun;156(6):1025-1035. doi: 10.1097/j.pain.0000000000000122. Pain. 2015. PMID: 25735002 Free PMC article.

5

Enhancing inactivation rather than reducing activation of Nav1.7 channels by a clinically effective analgesic CNV1014802.

Zheng YM, Wang WF, Li YF, Yu Y, Gao ZB. Zheng YM, et al. Acta Pharmacol Sin. 2018 Apr;39(4):587-596. doi: 10.1038/aps.2017.151. Epub 2017 Nov 2. Acta Pharmacol Sin. 2018. PMID: 29094728 Free PMC article.

6

Inhibitory effects of lappaconitine on the neuronal isoforms of voltage-gated sodium channels.

Li YF, Zheng YM, Yu Y, Gan Y, Gao ZB. Li YF, et al. Among authors: zheng ym. Acta Pharmacol Sin. 2019 Apr;40(4):451-459. doi: 10.1038/s41401-018-0067-x. Epub 2018 Jul 10. Acta Pharmacol Sin. 2019. PMID: 29991710 Free PMC article.

7

Discovery of aryl sulfonamide-selective Nav1.7 inhibitors with a highly hydrophobic ethanoanthracene core.

Wang JT, Zheng YM, Chen YT, Gu M, Gao ZB, Nan FJ. Wang JT, et al. Acta Pharmacol Sin. 2020 Mar;41(3):293-302. doi: 10.1038/s41401-019-0267-z. Epub 2019 Jul 17. Acta Pharmacol Sin. 2020. PMID: 31316182 Free PMC article.

8

Antiepileptic geissoschizine methyl ether is an inhibitor of multiple neuronal channels.

Xie ZQ, Tian XT, Zheng YM, Zhan L, Chen XQ, Xin XM, Huang CG, Gao ZB. Xie ZQ, et al. Acta Pharmacol Sin. 2020 May;41(5):629-637. doi: 10.1038/s41401-019-0327-4. Epub 2020 Jan 7. Acta Pharmacol Sin. 2020. PMID: 31911638 Free PMC article.

9

CCT128930 is a novel and potent antagonist of TRPM7 channel.

Guan Z, Chen X, Fang S, Ji Y, Gao Z, Zheng Y. Guan Z, et al. Among authors: zheng y. Biochem Biophys Res Commun. 2021 Jun 30;560:132-138. doi: 10.1016/j.bbrc.2021.04.119. Epub 2021 May 11. Biochem Biophys Res Commun. 2021. PMID: 33989904

10

(-)-Naringenin 4',7-dimethyl Ether Isolated from Nardostachys jatamansi Relieves Pain through Inhibition of Multiple Channels.

Gu RR, Meng XH, Zhang Y, Xu HY, Zhan L, Gao ZB, Yang JL, Zheng YM. Gu RR, et al. Among authors: zheng ym. Molecules. 2022 Mar 7;27(5):1735. doi: 10.3390/molecules27051735. Molecules. 2022. PMID: 35268839 Free PMC article.

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