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Rhesus macaques develop metabolic syndrome with reversible vascular dysfunction responsive to pioglitazone.
Zhang X, Zhang R, Raab S, Zheng W, Wang J, Liu N, Zhu T, Xue L, Song Z, Mao J, Li K, Zhang H, Zhang Y, Han C, Ding Y, Wang H, Hou N, Liu Y, Shang S, Li C, Sebokova E, Cheng H, Huang PL. Zhang X, et al. Among authors: zheng w. Circulation. 2011 Jul 5;124(1):77-86. doi: 10.1161/CIRCULATIONAHA.110.990333. Epub 2011 Jun 20. Circulation. 2011. PMID: 21690491 Free PMC article.
Eplerenone restores 24-h blood pressure circadian rhythm and reduces advanced glycation end-products in rhesus macaques with spontaneous hypertensive metabolic syndrome.
Zhang Y, Zheng W, Liu Y, Wang J, Peng Y, Shang H, Hou N, Hu X, Ding Y, Xiao Y, Wang C, Zeng F, Mao J, Zhang J, Ma D, Sun X, Li C, Xiao RP, Zhang X. Zhang Y, et al. Among authors: zheng w. Sci Rep. 2016 Apr 1;6:23957. doi: 10.1038/srep23957. Sci Rep. 2016. PMID: 27032687 Free PMC article.
Deficiency of PRKD2 triggers hyperinsulinemia and metabolic disorders.
Xiao Y, Wang C, Chen JY, Lu F, Wang J, Hou N, Hu X, Zeng F, Ma D, Sun X, Ding Y, Zhang Y, Zheng W, Liu Y, Shang H, Zhu W, Han C, Zhang Y, Ouyang K, Chen L, Chen J, Xiao RP, Li CY, Zhang X. Xiao Y, et al. Among authors: zheng w. Nat Commun. 2018 May 22;9(1):2015. doi: 10.1038/s41467-018-04352-z. Nat Commun. 2018. PMID: 29789568 Free PMC article.
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