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E2F1 Mediates SOX17 Deficiency-Induced Pulmonary Hypertension.
Yi D, Liu B, Ding H, Li S, Li R, Pan J, Ramirez K, Xia X, Kala M, Ye Q, Lee WH, Frye RE, Wang T, Zhao Y, Knox KS, Glembotski CC, Fallon MB, Dai Z. Yi D, et al. Among authors: zhao y. Hypertension. 2023 Nov;80(11):2357-2371. doi: 10.1161/HYPERTENSIONAHA.123.21241. Epub 2023 Sep 22. Hypertension. 2023. PMID: 37737027
Two distinct E3 ligases, SCFFBXL19 and HECW1, degrade thyroid transcription factor 1 in normal thyroid epithelial and follicular thyroid carcinoma cells, respectively.
Liu J, Dong S, Wang H, Li L, Ye Q, Li Y, Miao J, Jhiang S, Zhao J, Zhao Y. Liu J, et al. Among authors: zhao j, zhao y. FASEB J. 2019 Sep;33(9):10538-10550. doi: 10.1096/fj.201900415R. Epub 2019 Jun 25. FASEB J. 2019. PMID: 31238008 Free PMC article.
This study reveals an undiscovered molecular mechanism by which TTF1 ubiquitination and degradation is regulated by different E3 ligases in thyroid normal and tumor cells.-Liu, J., Dong, S., Wang, H., Li, L., Ye, Q., Li, Y., Miao, J., Jhiang, S., Zhao, J., Zhao …
This study reveals an undiscovered molecular mechanism by which TTF1 ubiquitination and degradation is regulated by different E3 ligases in …
SCF FBXW17 E3 ubiquitin ligase regulates FBXL19 stability and cell migration.
Dong S, Wei J, Bowser RK, Chen BB, Mallampalli RK, Miao J, Ye Q, Tran KC, Zhao Y, Zhao J. Dong S, et al. Among authors: zhao j, zhao y. J Cell Biochem. 2021 Apr;122(3-4):326-334. doi: 10.1002/jcb.29860. Epub 2020 Oct 14. J Cell Biochem. 2021. PMID: 33053230 Free PMC article.
ISGylation of NF-κBp65 by SCFFBXL19 E3 Ligase Diminishes Endothelial Inflammation.
Li L, Miao J, Shaheen N, Taleb SJ, Hu J, Ye Q, He J, Yan J, Mallampalli RK, Zhao J, Zhao Y. Li L, et al. Among authors: zhao j, zhao y. Arterioscler Thromb Vasc Biol. 2023 May;43(5):674-683. doi: 10.1161/ATVBAHA.122.318894. Epub 2023 Mar 30. Arterioscler Thromb Vasc Biol. 2023. PMID: 36994728 Free PMC article.
Molecular Regulation of Transforming Growth Factor-β1-induced Thioredoxin-interacting Protein Ubiquitination and Proteasomal Degradation in Lung Fibroblasts: Implication in Pulmonary Fibrosis.
Taleb SJ, Ye Q, Baoyinna B, Dedad M, Pisini D, Parinandi NL, Cantley LC, Zhao J, Zhao Y. Taleb SJ, et al. Among authors: zhao j, zhao y. J Respir Biol Transl Med. 2024 Mar;1(1):10002. doi: 10.35534/jrbtm.2024.10002. Epub 2024 Feb 1. J Respir Biol Transl Med. 2024. PMID: 38529321 Free PMC article.
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