Zhao Y - Search Results

1

Discovery of potent human dihydroorotate dehydrogenase inhibitors based on a benzophenone scaffold.

Li C, Zhou Y, Xu J, Zhou X, Liu S, Huang Z, Qiu Z, Zeng T, Gou K, Tao L, Zhong X, Yang X, Zhou Y, Su N, Chen Q, Zhao Y, Luo Y. Li C, et al. Among authors: zhao y. Eur J Med Chem. 2022 Dec 5;243:114737. doi: 10.1016/j.ejmech.2022.114737. Epub 2022 Sep 8. Eur J Med Chem. 2022. PMID: 36115209

2

Syntheses and cell-based phenotypic screen of novel 7-amino pyrido[2,3-d]pyrimidine-6-carbonitrile derivatives as potential antiproliferative agents.

Yang T, He H, Ang W, Yang YH, Yang JZ, Lin YN, Yang HC, Pi WY, Li ZC, Zhao YL, Luo YF, Wei Y. Yang T, et al. Among authors: zhao yl. Molecules. 2012 Feb 24;17(3):2351-66. doi: 10.3390/molecules17032351. Molecules. 2012. PMID: 22367029 Free PMC article.

3

Synthesis and evaluation of 2-[2-(phenylthiomethyl)-1H-benzo[d] imidazol-1-yl)acetohydrazide derivatives as antitumor agents.

Liu T, Sun C, Xing X, Jing L, Tan R, Luo Y, Huang W, Song H, Li Z, Zhao Y. Liu T, et al. Among authors: zhao y. Bioorg Med Chem Lett. 2012 May 1;22(9):3122-5. doi: 10.1016/j.bmcl.2012.03.061. Epub 2012 Mar 21. Bioorg Med Chem Lett. 2012. PMID: 22483608

4

Synthesis and biological evaluation of novel benzamide derivatives as potent smoothened antagonists.

Wu TM, Wang DC, Xiang P, Zhang JN, Sang YX, Lin HJ, Chen J, Xie G, Song H, Zhao YL, Xie YM. Wu TM, et al. Bioorg Med Chem Lett. 2014 Mar 1;24(5):1426-31. doi: 10.1016/j.bmcl.2014.01.006. Epub 2014 Jan 15. Bioorg Med Chem Lett. 2014. PMID: 24491459

5

Design, Synthesis, and Structure-Activity Relationship Studies of 3-(Phenylethynyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine Derivatives as a New Class of Src Inhibitors with Potent Activities in Models of Triple Negative Breast Cancer.

Zhang CH, Zheng MW, Li YP, Lin XD, Huang M, Zhong L, Li GB, Zhang RJ, Lin WT, Jiao Y, Wu XA, Yang J, Xiang R, Chen LJ, Zhao YL, Cheng W, Wei YQ, Yang SY. Zhang CH, et al. Among authors: zhao yl. J Med Chem. 2015 May 14;58(9):3957-74. doi: 10.1021/acs.jmedchem.5b00270. Epub 2015 Apr 16. J Med Chem. 2015. PMID: 25835317

6

5-Methoxyquinoline Derivatives as a New Class of EZH2 Inhibitors.

Xiang P, Jie H, Zhou Y, Yang B, Wang HJ, Hu J, Hu J, Yang SY, Zhao YL. Xiang P, et al. Among authors: zhao yl. Molecules. 2015 Apr 27;20(5):7620-36. doi: 10.3390/molecules20057620. Molecules. 2015. PMID: 25923513 Free PMC article.

7

Synthesis and biological evaluation of novel (E)-N'-(2,3-dihydro-1H-inden-1-ylidene) benzohydrazides as potent LSD1 inhibitors.

Zhou Y, Li Y, Wang WJ, Xiang P, Luo XM, Yang L, Yang SY, Zhao YL. Zhou Y, et al. Among authors: zhao yl. Bioorg Med Chem Lett. 2016 Sep 15;26(18):4552-4557. doi: 10.1016/j.bmcl.2015.06.054. Epub 2015 Jun 20. Bioorg Med Chem Lett. 2016. PMID: 27524309

8

ZY0511, a novel, potent and selective LSD1 inhibitor, exhibits anticancer activity against solid tumors via the DDIT4/mTOR pathway.

Li Y, Tao L, Zuo Z, Zhou Y, Qian X, Lin Y, Jie H, Liu C, Li Z, Zhang H, Zhang H, Cen X, Yang S, Zhao Y. Li Y, et al. Among authors: zhao y. Cancer Lett. 2019 Jul 10;454:179-190. doi: 10.1016/j.canlet.2019.03.052. Epub 2019 Apr 10. Cancer Lett. 2019. PMID: 30978443

9

A novel series of human dihydroorotate dehydrogenase inhibitors discovered by in vitro screening: inhibition activity and crystallographic binding mode.

Zeng T, Zuo Z, Luo Y, Zhao Y, Yu Y, Chen Q. Zeng T, et al. Among authors: zhao y. FEBS Open Bio. 2019 Aug;9(8):1348-1354. doi: 10.1002/2211-5463.12658. Epub 2019 May 29. FEBS Open Bio. 2019. PMID: 31087527 Free PMC article.

10

Corrigendum to "ZY0511, a novel, potent and selective LSD1 inhibitor, exhibits anticancer activity against solid tumors via the DDIT4/mTOR pathway" [Cancer Lett. 454 (2019) 179-190].

Li Y, Tao L, Zuo Z, Zhou Y, Qian X, Lin Y, Jie H, Liu C, Li Z, Zhang H, Zhang H, Cen X, Yang S, Zhao Y. Li Y, et al. Among authors: zhao y. Cancer Lett. 2019 Oct 1;461:153-154. doi: 10.1016/j.canlet.2019.05.002. Epub 2019 May 16. Cancer Lett. 2019. PMID: 31103248 No abstract available.

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